VILIP-1 / VSNL1 Protein (Native)

13.05.2013

Sino Biological Inc. liefert VILIP-1 / VSNL1 Protein (Native) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über VILIP-1 / VSNL1 Protein (Native) lesen Sie bitte: http://www.sinobiological.com/VILIP-1-VSNL1-Protein-Antibody-a-5913.html

Produkt-Information von VILIP-1 / VSNL1 Protein

Synonym	VSNL1, VISL1
Protein Construction	A DNA sequence encoding human VSNL1 (Gly2-Lys191) was expressed with a N-terminal Met.
Source	Human
Expression Host	E.coli

QC Testing von VILIP-1 / VSNL1 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: VSNL1 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met
Molecular Mass	The recombinant human VSNL1 consists of 191 amino acids and predicts a molecular mass of 22.1 KDa. It migrates as an approximately 19 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von VILIP-1 / VSNL1 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von VILIP-1 / VSNL1 Protein

VILIP-1, also known as VSNL1, is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. VILIP-1 gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

References

Burgoyne RD. 2007, Nat Rev Neurosci. 8 (3): 182-93.
Kose A. et al., 1990, Brain Res. 518 (1-2): 209-17.
Polymeropoulos MH. et al., 1996, Genomics. 29 (1): 273-5.