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| Immunogen | Recombinant human TIMP1 protein ( Catalog #10934-H08H ) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 004 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human TIMP1 ( rh TIMP1; Catalog#10934-H08H ; NP_003245.1 ; Met 1 - Ala 207 ). |
| Specificity | Human TIMP1 |
| No cross-reactivity in ELISA with Human TIMP2 | |
| Western blot | This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect human TIMP1 in WB. Using a DAB detection system, the detection limit for human TIMP1 is approximately 1 ng/lane under non-reducing conditions and 10 ng/lane under reducing conditions |
| Direct ELISA | This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human TIMP1. The detection limit for human TIMP1 is approximately 0.00975 ng/well |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Enzyme>>Protease & Regulator>>Metalloprotease & Regulator>>Tissue Inhibitor of Metalloproteinase>>TIMP-1/TIMP1
Cancer>>Angiogenesis>>Tissue Inhibitor of Metalloproteinase>>TIMP-1/TIMP1
Cancer>>Cancer Biomarkers>>TIMP-1/TIMP1
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| TIMP-1/TIMP1 | Human | TIMP-1/TIMP1 Protein, Recombinant | 10934-H08H |
| TIMP-1/TIMP1 | Human | TIMP1/TIMP1 Protein, Recombinant | 10934-HNAH |
| TIMP-1/TIMP1 | Mouse | TIMP-1/TIMP1 Protein, Recombinant | 50342-MNAH |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human TIMP-1/TIMP1 | ELISA | Mouse Monoclonal Antibody | 10934-MM02 |
| Human TIMP-1/TIMP1 | WB, ELISA | Mouse Monoclonal Antibody | 10934-MM03 |
| Human TIMP-1/TIMP1 | ELISA | Rabbit Polyclonal Antibody | 10934-RP01 |
| Human TIMP-1/TIMP1 | WB | Rabbit Polyclonal Antibody(Antigen Affinity Purified) | 10934-RP04 |
Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. The TIMP family encompasses four members (TIMP1-4), and the inducible form TIMP-1/TIMP1 is a 28 kDa glycoprotein expressed by a variety of cell types. It inhibits most MMPs except membrane-type MMP subfamily by forming non-covalent binary complex, but also interacts with the hemopexin-like (PEX) domain of pro MMP-9. TIMP-1/TIMP1 has been identified as a multifunctional molecule with divergent functions. It exhibits keratinocyte and fibroblast growth factor-like activity and acts as a cell survival factor, and additionally participates in tumor metastasis, angiogenesis, inflammatory responses, as well as CNS homeostasis. Thus, TIMP-1/TIMP1 overexpression may serve to help identify patients with particularly aggressive disease for adjuvant treatments.
Sino Biological Inc. liefert TIMP1 / EPA /CLGI Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über TIMP1 / EPA /CLGI Antikörper lesen Sie bitte: http://www.sinobiological.com/TIMP-1-Antibody-g-6051.html
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