IFN-gamma / IFNG Antikörper

05.01.2012

Produkt-Information von IFN-gamma / IFNG Antikörper

Immunogen	Recombinant human IFNG protein ( Catalog#11725-HNAC )
Antibody Type	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID	121
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human IFNG ( rh IFNG ; Catalog#11725-HNAC ; NP_000610.2 ; Met 1 - Gln 166 ).

Usage Guide von IFN-gamma / IFNG Antikörper

Specificity	Human IFN-gamma / IFNG
Western blot	This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect human IFN-gamma in WB. Using a DAB detection system, the detection limit for human IFN-gamma is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions
Direct ELISA	This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect human IFN-gamma. The detection limit for human IFN-gamma is approximately 0.00245 ng/well
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von IFN-gamma / IFNG Antikörper

Related Areas:

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-10/Interferon Family>>IFN gamma/IFNG

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
IFN gamma/IFNG	Human	IFN gamma/IFNG Protein, Recombinant	11725-HNAC
IFN gamma/IFNG	Mouse	IFN gamma/IFNG Protein, Recombinant	50709-M02H
IFN gamma/IFNG	Mouse	IFN gamma/IFNG Protein, Recombinant	50709-M08H
IFN gamma/IFNG	Rat	IFNG / Interferon Gamma Protein, Recombinant	80234-R02H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human IFN gamma/IFNG	WB, ELISA	IFN gamma/IFNG Antibody, Rabbit MAb	11725-R121
Human IFN gamma/IFNG	WB, ELISA	IFN gamma/IFNG Antibody, Rabbit PAb	11725-RP01
Human IFN gamma/IFNG	WB, ELISA	IFN gamma/IFNG Antibody, Rabbit PAb (Antigen Affinity Purified)	11725-RP02

Hintergrund von IFN-gamma / IFNG Antikörper

Interferon gamma, also known as IFN-gamma, Immune interferon and IFNG, is a secreted protein which belongs to the type I I (or gamma) interferon family. IFN-gamma / IFNG is produced by lymphocytes and activated by specific antigens or mitogens. IFN-gamma / IFNG, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. Genetic variation in IFNG is associated with the risk of aplastic anemia (AA) which is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.

References

Rinderknecht E. et al., 1984, J. Biol. Chem. 259:6790-7.
Landar A. et al., 2000, J. Mol. Biol. 299:169-79.
Dufour C. et al., 2004, Br. J. Haematol. 126:682-5.
Goshima N. et al., 2008, Nat. Methods 5:1011-7.

Sino Biological Inc. liefert IFN-gamma / IFNG Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über IFN-gamma / IFNG Antikörper lesen Sie bitte: http://www.sinobiological.com/IFN-gamma-Antibody-g-6052.html