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| Immunogen | Recombinant mouse CD8a protein ( Catalog#50389-M08H ) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 012 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant mouse CD8a extracellular domain ( rM CD8a ; Catalog#50389-M08H ; NP_001074579.1 ; Met 1 - Tyr 196 ). |
| Specificity | Mouse CD8a / Lyt2 |
| Western blot | This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect mouse CD8A in WB.Using a DAB detection system, the detection limit for mouse CD8A is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions |
| Direct ELISA | This antibody can be used at 0.1 - 0.2 μg/mL with the appropriate secondary reagents to detect mouse CD8A. The detection limit for mouse CD8A is approximately 0.0195 ng/well |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Immunology>>Cluster of Differentiation>>CD8a
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CD8a | Human | CD8a Protein, Recombinant | 10980-H08H |
| CD8a | Mouse | CD8a Protein, Recombinant | 50389-M08H |
| CD8a | Ferret | CD8a Protein, Recombinant | 60001-F08H |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human CD8a | WB, ELISA | CD8a Antibody, Mouse Mab | 10980-MM04 |
| Mouse CD8a | WB, ELISA | CD8a Antibody, Rabbit MAb | 50389-R012 |
| Mouse CD8a | WB, ELISA | Rabbit Polyclonal Antibody | 50389-RP01 |
| Mouse CD8a | WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 50389-RP02 |
| Mouse CD8a | FCM | CD8a Antibody ( FITC ) | 50389-R208-F |
Mouse T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
Sino Biological Inc. liefert CD8a / Lyt2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CD8a / Lyt2 Antikörper lesen Sie bitte: http://www.sinobiological.com/CD8a-Antibody-g-6050.html
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