STC2 / Stanniocalcin 2 Protein

Sino Biological Inc. liefert STC2 / Stanniocalcin 2 Protein mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über STC2 / Stanniocalcin 2 Protein lesen Sie bitte: http://www.sinobiological.com/STC2-Stanniocalcin-2-Protein-g-10539.html

Produkt-Information von STC2 / Stanniocalcin 2 Protein

QC Testing von STC2 / Stanniocalcin 2 Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: STC2 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Thr 25
Molecular Mass	The recombinant human STC2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 519 amino acids and has a predicted molecular mass of 57.7 kDa. The apparent molecular mass of the protein is approximately 63 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von STC2 / Stanniocalcin 2 Protein

Verwandte Produkte & Themen von STC2 / Stanniocalcin 2 Protein

Beschreibung von STC2 / Stanniocalcin 2 Protein

STC2 has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. It is a secreted, homodimeric glycoprotein which expressed in a wide variety of tissues. STC2 has an anti-hypocalcemic action on calcium and phosphate homeostasis. It may have autocrine or paracrine functions. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. STC2 may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis.

References

1. Chang AC. et al., 1998, Mol Cell Endocrinol. 141 (1-2): 95-9.
2. Ishibashi K. et al., 1998, Biochem Biophys Res Commun. 250 (2): 252-8.
3. Uo CW. et al., 2005, Endocrinology. 146 (1): 469-76.

STC2 related areas, pathways, and other information