SerpinF2 Antikörper

20.08.2012

Produkt-Information von SerpinF2 Antikörper

Immunogen	Recombinant Human SerpinF2 protein (Catalog#10297-H08H)
Antibody Type	Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
Clone ID	043
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinF2 (rh SerpinF2; Catalog#10297-H08H; NP_000925.2; Met 1-Lys 491).

Usage Guide von SerpinF2 Antikörper

Specificity

Human SerpinF2

No cross-reactivity in ELISA with

Human SerpinA1

Human SerpinA5

Mouse SerpinD1

Mouse SerpinF1

Mouse SerpinF2

Immunochemistry

IHC-P: 1-10 μg/mL

SerpinF2-brain immunohistochemistry

Immunochemical staining of human SerpinF2 in human brain with rabbit monoclonal antibody (5 μg/mL, formalin-fixed paraffin embedded sections).

Direct ELISA

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human SerpinF2.

Storage

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von SerpinF2 Antikörper

Related Areas:

Enzyme>>Protease & Regulator>>Serine Protease & Regulator>>Serpin Superfamily>>SerpinF2

Immunology>>Innate Immunity>>Coagulation>>SerpinF2

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
SerpinF2	Human	SerpinF2 Protein, Recombinant	10297-H08H
SerpinF2	Mouse	SerpinF2 Protein, Recombinant	50167-M08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human SerpinF2	WB, ELISA	SerpinF2 Antibody, Mouse MAb	10297-MM05
Human SerpinF2	WB, ELISA	SerpinF2 Antibody, Rabbit PAb	10297-RP01
Human SerpinF2	WB, ELISA	SerpinF2 Antibody, Rabbit PAb (Antigen Affinity Purified)	10297-RP02
Human SerpinF2	ELISA, IHC-P	SerpinF2 Antibody	10297-R043
Mouse SerpinF2	WB, ELISA	Rabbit Monoclonal Antibody	50167-R128
Mouse SerpinF2	WB, ELISA	Rabbit Polyclonal Antibody	50167-RP01
Mouse SerpinF2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	50167-RP02

Hintergrund von SerpinF2 Antikörper

SerpinF2, also known as alpha-2 antiplasmin (alpha-2 AP), is a member of the Serpin superfamily. SerpinF2 is the principal physiological inhibitor of serine protease plasmin, and as well as, an efficient inhibitor of trypsin and chymotrypsin. This protease is produced mainly by liver and kidney, and also expressed at moderate level in other tissues such as muscle, intestine, central nervous system and placenta. Alpha-2 AP is an unusual serpin in that it contains extensive N- and C-terminal sequences flanking the serpin domain. The N-terminal sequence is crosslinked to fibrin by factor XIIIa, whereas the C-terminal region mediates the initial interaction with plasmin. Alpha-2 AP plays the dominant role in inhibiting both plasma clot lysis and thrombus lysis, and accordingly, the deficiency of Alpha-2 antiplasmin in humans results in uncontrolled fibrinolysis and a bleeding disorder.

References

Potempa, J. et al., 1988, Science. 241: 699-700.
Menoud, P.A. et al., 1996, J. Clin. Invest. 97: 2478-2484.
Mutch, NJ. et al., 2007, J. Thromb. Haemost. 5: 812-817.
Victoria, J. et al., 2007, Blood, 109: 5286-5292.

Sino Biological Inc. liefert SerpinF2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über SerpinF2 Antikörper lesen Sie bitte: http:www.sinobiological.com/SerpinF2-Antibody-g-9360.html