C1D Antikörper (Antigen Affinity Purified)

20.08.2012

Produkt-Information von C1D Antikörper

Immunogen	Recombinant Human C1D protein (Catalog#12432-H09E)
Antibody Type	Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type	Rabbit IgG
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	Produced in rabbits immunized with purified, recombinant Human C1D (rh C1D; Catalog#12432-H09E; Q13901; Met 1-Ser 141). C1D specific IgG was purified by Human C1D affinity chromatography.

Usage Guide von C1D Antikörper

Specificity

Human C1D

Immunochemistry

IHC-P: 0.1-2 μg/mL

C1D-kidney immunohistochemistry

Immunochemical staining of human C1D in human kidney with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections).
The left panel: tissue incubated with primary antibody;
The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).

Direct ELISA

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human C1D. The detection limit for Human C1D is approximately 0.00245 ng/well.

Storage

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Hintergrund von C1D Antikörper

C1D nuclear receptor corepressor is a member of the C1D family. As a DNA binding and apoptosis-inducing protein, C1D nuclear receptor corepressor interacts with TSNAX and DNA-PKcs. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. C1D nuclear receptor corepressor acts as a corepressor for the thyroid hormone receptor. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. It potentiates transcriptional repression by NR1D1 and THRB. C1D nuclear receptor corepressor can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. It also can induce apoptosis in a p53/TP53 dependent manner.

References

Schilders G. et al., 2007, Arthritis Rheum. 56 (7): 2449-54.
Schilders G. et al., 2007, Nucleic Acids Res. 35 (8): 2564-72.
Erdemir T. et al., 2002, J Cell Sci. 115 (1): 207-16.

Sino Biological Inc. liefert C1D Antikörper (Antigen Affinity Purified) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über C1D Antikörper (Antigen Affinity Purified) lesen Sie bitte: http:www.sinobiological.com/C1D-Antibody-g-9361.html

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
C1D	Human	C1D Protein, Recombinant, with GST Tag	12432-H09E

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat No
Human C1D	ELISA IHC-P	C1D Antibody (Antigen Affinity Purified)	12432-RP02

C1D Antikörper (Antigen Affinity Purified)

Produkt-Information von C1D Antikörper

Usage Guide von C1D Antikörper

Verwandte Produkte & Themen von C1D Antikörper

Hintergrund von C1D Antikörper

References