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| Immunogen | Recombinant Human CHI3L1 / YKL40 protein (Catalog#11227-H08H) |
| Antibody Type | Mouse Monoclonal Antibody ( Mouse mAb Service Platform ) |
| Clone ID | 04 |
| Ig Type |
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| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CHI3L1 / YKL40 (rh CHI3L1 / YKL40; Catalog#11227-H08H; NP_001267.2; Met 1-Thr 383). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Specificity | Human CHI3L1 / YKL40 | ||
| Immunochemistry | IHC-P 10-30 μg/mL
| ||
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Enzyme>>Carbohydrate Metabolism Enzymes>>CHI3L1
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CHI3L1/YKL40 | Human | CHI3L1/YKL40 Protein, Recombinant | 11227-H08H |
| CHI3L1/YKL40 | Mouse | CHI3L1 / gp39 Protein, Recombinant | 50929-M08H |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human CHI3L1/YKL40 | WB, ELISA | CHI3L1 / YKL40 Antibody | 11227-RP01 |
| Human CHI3L1/YKL40 | WB, ELISA | CHI3L1 / YKL40 Antibody (Antigen Affinity Purified) | 11227-RP02 |
| Human CHI3L1/YKL40 | IHC-P | CHI3L1 / YKL40 Antibody | 11227-MM04 |
Chitinase-3-like protein 1, also known as Cartilage glycoprotein 39, and CHI3L1, is a member of the glycosyl hydrolase 18 family. The principal sources of CHI3L1 are activated macrophages and chondrocytes, neutrophils, and some tissue and tumor cells. CHI3L1 is a secreted glycoprotein that is upregulated in a number of human cancers and in non-neoplastic disease states characterized by chronic inflammation and tissue remodeling. Increased serum levels of CHI3L1 parallel disease severity, poorer prognosis, and shorter survival in many human neoplasias, including cancers of the breast, colon, prostate, ovaries, brain, thyroid, lung, and liver. Increased serum CHI3L1 also correlates with disease severity in rheumatoid arthritis, osteoarthritis, liver fibrosis, inflammatory bowel disease, and bacterial septicemia. CHI3L1 can act as a fibroblast mitogen and can activate several signaling pathways. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheumatoid arthritis, osteoarthritis, scleroderma, and cirrhosis of the liver. The ability of CHI3L1 to bind both proteins and carbohydrates allows potential interactions with a variety of cell-surface and extracellular-matrix proteins, proteoglycans, and polysaccharides, and thus CHI3L1 can interface between proteomics and glycomics. CHI3L1 may play an important role in the capacity of cells to respond to and cope with changes in their environment.
Sino Biological Inc. liefert CHI3L1 / YKL40 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CHI3L1 / YKL40 Antikörper lesen Sie bitte: http:www.sinobiological.com/CHI3L1-YKL40-Antibody-g-9359.html
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