RCAS1 / EBAG9 Protein (His Tag)

06.05.2013

Sino Biological Inc. liefert RCAS1 / EBAG9 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über RCAS1 / EBAG9 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/RCAS1-EBAG9-Protein-Antibody-a-5917.html

Produkt-Information von RCAS1 / EBAG9 Protein

Synonym	EBAG9, RCAS1
Protein Construction	A DNA sequence encoding the mature form of human EBAG9 (O00559) (Arg28-Ser213) was expressed with a polyhistidine tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von RCAS1 / EBAG9 Protein

Purity	> 90 % as determined by SDS-PAGE	SDS-PAGE: RCAS1 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human EBAG9 consists of 201 amino acids and predicts a molecular mass of 23 KDa. It migrates as an approximately 33 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von RCAS1 / EBAG9 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von RCAS1 / EBAG9 Protein

RCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

References

Ohshima K. et al., 2001, Clin Exp Immunol. 123 (3): 481-6.
Ikeda K. et al., 2000, Biochem Biophys Res Commun. 273 (2): 654-60.
Nakashima M. et al., 1999, Nat Med. 5 (8): 938-42.