MID1IP1 Protein (His Tag)

06.05.2013

Sino Biological Inc. liefert MID1IP1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über MID1IP1 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/MID1IP1-Protein-Antibody-a-5931.html

Produkt-Information von MID1IP1 Protein

Synonym	MID1IP1, MIG12
Protein Construction	A DNA sequence encoding the human MID1IP1 (Q9NPA3 ) (Met1-His183) was expressed with a polyhistidine tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von MID1IP1 Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: MID1IP1 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human MID1IP1 consists of 198 amino acids and predicts a molecular mass of 22 KDa. It migrates as an approximately 28 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 50mM Tris, 100mM NaCl, 10% Glycerol, pH 8.0. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von MID1IP1 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von MID1IP1 Protein

MID1IP1 belongs to the SPOT14 family. It is a homodimer in the absence of THRSP. MID1IP1 interacts with ACACA and ACACB. It plays a role in the regulation of lipogenesis in liver. It up-regulates ACACA enzyme activity. MID1IP1 is required for efficient lipid biosynthesis, including triacylglycerol, diacylglycerol and phospholipid. MID1IP1 is involved in stabilization of microtubules. Its interaction with THRSP interferes with ACACA binding.

References

Aipoalani DL. et al., 2010, Endocrinology. 151 (5): 2071-7.
Colbert CL. et al., 2010, Proc Natl Acad Sci. 107 (44): 18820-5.
Inoue J. et al., 2011, Mol Endocrinol. 25 (6): 995-1005.