Rat THY1 Protein (His Tag)

Sino Biological Inc. liefert Rat THY1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat THY1 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/THY1-Protein-g-10045.html

Produkt-Information von THY1 Protein

QC Testing von THY1 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: THY1 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Gln 20
Molecular Mass	The recombinant rat THY1 comprises 121 amino acids and predicts a molecular mass of 14.1 kDa. The apparent molecular mass of  the recombinant protein is approximately 27-29 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von THY1 Protein

Verwandte Produkte & Themen von THY1 Protein

Biomarkers>>Neuronal Cell Markers>>CD90/THY-1

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD90/THY-1

Immunology>>Cluster of Differentiation>>Hematopoietic Stem Cell CD Marker>>CD90/THY-1

Beschreibung von THY1 Protein

Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. THY1 / CD90, a member of the immunoglobulin superfamily of adhesion molecules with constitutive expression on fibroblast cells. THY1 / CD90 is a cell surface glycoprotein originally identified on mouse thymocytes. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. THY1 / CD90 is a membrane glycoprotein expressed in thymus, retinal ganglionic cells, and several types of stem cells. It was observed that THY1 / CD90 cell surface expression decreased significantly during the course of infection. In adult rats, expression of THY1 / CD90 on the B cell lineage is confined to immature B cells. The expression of THY1 / CD90 on neonatal MZ-B cells may have implications for their responsiveness to polysaccharide (T cell-independent type 2) antigens. THY1 / CD90 is modulated following infection with Human cytomegalovirus (HCMV). Neuroblastoma (NBL) is the most common solid tumor in children. THY1 / CD90 seemed to be a marker with a specific prognostic value in NBL patients. THY1 / CD90 may also play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

References

1. Dammers PM. et al., 2002, Dev Immunol. 9 (4): 187-95.
2. Leis M. et al., 2004, J Gen Virol. 85 (7): 1995-2000.
3. Wiesmann A. et al., 2006, Head Face Med. 2: 8.
4. Fiegel HC. et al., 2008, Pediatr Surg Int. 24 (1): 101-5.
5. Kisselbach L. et al., 2009, Cytotechnology. 59 (1): 31-44.