Rat REG1A / PSPS Protein

Sino Biological Inc. liefert Rat REG1A / PSPS Protein mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat REG1A / PSPS Protein lesen Sie bitte: http://www.sinobiological.com/REG1A-PSPS-Protein-g-9957.html

Produkt-Information von REG1A / PSPS Protein

QC Testing von REG1A / PSPS Protein

Purity	> (55.3+31.4)% as determined by SDS-PAGE	SDS-PAGE: REG1A protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Leu 23
Molecular Mass	The recombinant rat REG1A /Fc is a disulfide-linked homodimer. The reduced monomer comprises 319 amino acids and has a predicted molecular mass of 35.8 kDa. The apparent molecular mass of the protein is approximately 40 and 43 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von REG1A / PSPS Protein

Verwandte Produkte & Themen von REG1A / PSPS Protein

Immunology>>Adhesion Molecule>>Lectin>>REG1A

Beschreibung von REG1A / PSPS Protein

Lithostathine-1-alpha, also known as Pancreatic stone protein, Pancreatic thread protein, Regenerating islet-derived protein 1-alpha, REG1A, REG-1-alpha, and PSPS, is highly expressed in fetal and infant brains. REG1A contains one C-type lectin domain and is a known growth factor affecting pancreatic islet beta cells. REG1A may act as an inhibitor of spontaneous calcium carbonate precipitation. It may also be associated with neuronal sprouting in brain, and with brain and pancreas regeneration. REG1A has been reported to be expressed in human cancers, and it may be positively correlated with patient's prognosis. REG3A and REG1A proteins are both involved in liver and pancreatic regeneration and proliferation. High levels of REG1A expression by tumor cells are an independent predictor of a poor prognosis in patients with non-small cell lung cancer (NSCLC).

References

1. Gerbaud V. et al.,2000, J Biol Chem. 275: 1057-64.
2. Cavard C. et al., 2006, Oncogene. 25 (4): 599-608.
3. Astrosini C. et al., 2008, Int J Cancer. 123 (2): 409-13.
4. Minamiya Y. et al., 2008, Lung Cancer. 60 (1): 98-104.
5. Geng J. et al., 2009 Eur J Surg Oncol. 35 (8): 852-7.