Rat COL4A3 Protein

Sino Biological Inc. liefert Rat COL4A3 Protein mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat COL4A3 Protein lesen Sie bitte: http://www.sinobiological.com/COL4A3-Protein-g-10330.html

Produkt-Information von COL4A3 Protein

QC Testing von COL4A3 Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: COL4A3 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Glu
Molecular Mass	The recombinant rat COL4A3 comprises 505 amino acids and predicts a molecular mass of 55.2 kDa. The apparent molecular mass of  the recombinant protein is approximately 59 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von COL4A3 Protein

Verwandte Produkte & Themen von COL4A3 Protein

Beschreibung von COL4A3 Protein

COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix structure with 2 other subunits to form COL4A3. Autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli can cause goodpasture syndrome. COL4A3 is also linked to an autosomal recessive form of alport syndrome. COL4A3 is organized in a head-to-head conformation and each gene pair shares a common promoter.

References

1. Ghebrehiwet B. et al., 1992, J Leukoc Biol. 51 (6): 546-56.
2. Maziers N. et al., 2006, Nephrol Ther. 1 (2): 90-100.
3. Rana K. et al., 2005, Semin Nephrol. 25 (3): 163-70.