Rat CLMP / ACAM / ASAM Protein (His Tag)

25.10.2012

Produkt-Information von CLMP / ACAM / ASAM Protein

Synonym	ASAM, Clmp ,Acam
Protein Construction	A DNA sequence encoding the rat ASAM(Q8K1G0)(Met1-Met232) was expressed, fused with a polyhistidine tag at the C-terminus.
Source	Rat
Expression Host	Human Cells

QC Testing von CLMP / ACAM / ASAM Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: CLMP protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Thr 18
Molecular Mass	The recombinant rat ASAM comprises 226 amino acids and predicts a molecular mass of 25.6 kDa. The apparent molecular mass of the recombinant protein is approximately 37 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from a 0.2μm filtered solution of PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von CLMP / ACAM / ASAM Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Verwandte Produkte & Themen von CLMP / ACAM / ASAM Protein

Related Areas:

Immunology>>Adhesion Molecule>>Cell Adhesion Molecule (IgSF CAM)>>ASAM

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
ASAM	Human	ASAM Protein, Recombinant	10794-H08H
ASAM	Mouse	ASAM Protein, Recombinant	50553-M08H
ASAM	Rat	CLMP / ACAM / ASAM Protein	80219-R08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human ASAM	ELISA	ASAM/ACAM/CLMP Antibody, Mouse Mab	10794-MM05
Human ASAM	ELISA	Rabbit Polyclonal Antibody	10794-RP01
Human ASAM	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10794-RP02
Mouse ASAM	WB, ELISA	Rabbit Polyclonal Antibody	50553-R030
Mouse ASAM	WB, ELISA	Rabbit Polyclonal Antibody	50553-R001
Mouse ASAM	WB, ELISA	Rabbit Polyclonal Antibody	50553-RP02

Beschreibung von CLMP / ACAM / ASAM Protein

Adipocyte-specific adhesion molecule (ASAM), also known as ACAM and CLMP, is a type I transmembrane protein and a member of the CTX (cortical thymocyte marker in Xenopus) family within the immunoglobulin superfamily. The extracellular region of human ASAM contains two potential N-linked glycosylation sites, and two immunoglobulin domains, one variable (V-type) and one constant (C2-type), separated from each other by a J-segment. ASAM is highly expressed in the small intestine and placenta, and is found at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney, and lung, and appears in low levels in the liver and peripheral blood leukocytes as well. ASAM is a transmembrane component of tight junctions in epithelial cells that can mediate cell aggregation and regulate transepithelial resistance across polarized epithelial cells. Its expression is strongly correlated with white adipose tissue (WAT) mass of human and rodents with obesity. Human ASAM shares 94% and 93% aa sequence identity with rat and mouse ASAM, respectively.

References

Raschperger, E. et al., 2004, J. Biol. Chem. 279: 796-804.
Eguchi, J. et al., 2005, Biochem. J. 387: 343-353.

Sino Biological Inc. liefert Rat CLMP / ACAM / ASAM Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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