Rat CLEC4D / CLECSF8 Protein (His Tag)

20.09.2012

Produkt-Information von CLEC4D / CLECSF8 Protein

Synonym	CLEC4D, Clecsf8, Mcl
Protein Construction	A DNA sequence encoding the rat CLEC4D (Q69FH1) (Trp48-Lys218) was expressed, fused with a polyhistidine tag at the N-terminus.
Source	Rat
Expression Host	Human Cells

QC Testing von CLEC4D / CLECSF8 Protein

Purity	>88 % as determined by SDS-PAGE	SDS-PAGE: CLEC4D / CLECSF8 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant rat CLEC4D is a disulfide-linked homodimer. The reduced monomer comprises 191 amino acids and has a predicted molecular mass of 22.3 kDa. The apparent molecular mass of the protein is approximately 29 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from a 0.2μm filtered solution of PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von CLEC4D / CLECSF8 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

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Immunology>>Adhesion Molecule>>Lectin>> Sino Biological Inc. liefert Rat GDNF Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat GDNF Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/GDNF-Protein-g-9294.html CLEC4D/CLECSF8

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CLEC4D/CLECSF8	Human	CLEC4D/CLECSF8 Protein, Recombinant	11485-H07H
CLEC4D/CLECSF8	Rat	CLEC4D / CLECSF8 Protein, Recombinant	80213-R07H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CLEC4D/CLECSF8	WB, ELISA	CLEC4D Antibody	11485-R001

Beschreibung von CLEC4D / CLECSF8 Protein

C-type lectin domain family 4 member D, also known as C-type lectin superfamily member 8, C-type lectin-like receptor 6, CLEC4D and CLECSF8, is a single-pass type I I membrane protein which contains one C-type lectin domain. CLEC4D is expressed weakly in peripheral blood leukocytes, bone marrow and spleen. Expression of CLEC4D is confined mostly in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-alpha and IFN-gamma. CLEC4D contains one C-type lectin domain. A C-type lectin (CLEC) is a type of carbohydrate-binding protein domain known as a lectin. The C-type designation is from their requirement for calcium for binding. Proteins that contain C-type lectin domains have a diverse range of functions including cell-cell adhesion, immune response to pathogens and apoptosis. CLEC4D functions as an endocytic receptor. It may be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T cells.

References

Drickamer K. et al., 1999, Curr Opin Struct Biol. 9 (5): 585-90.
Walker JR. et al., 2004, Biochemistry. 43 (13): 3783-92.
Zelensky AN. et al., 2005, FEBS J. 272 (24): 6179–217.
Cambi A. et al., 2009, Curr Biol. 19 (9): R375-8.

Sino Biological Inc. liefert Rat CLEC4D / CLECSF8 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat CLEC4D / CLECSF8 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/CLEC4D-CLECSF8-Protein-g-9298.html