Rat CLEC4A3 Protein

27.04.2013

Sino Biological Inc. liefert Rat CLEC4A3 Protein mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat CLEC4A3 Protein lesen Sie bitte: http://www.sinobiological.com/CLEC4A3-Protein-Antibody-a-5854.html

Produkt-Information von CLEC4A3 Protein

Synonym	CLEC4A3
Protein Construction	A DNA sequence encoding the rat CLEC4A3(Q5YIS0) (Leu68-Leu237) was expressed with Fc region of human IgG1 at the N-terminus.
Source	Rat
Expression Host	Human Cells

QC Testing von CLEC4A3 Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: CLEC4A3 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Glu
Molecular Mass	The recombinant rat CLEC4A3 comprises 430 amino acids and predicts a molecular mass of 48.3 kDa. The apparent molecular mass of the recombinant protein is approximately 58 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von CLEC4A3 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von CLEC4A3 Protein

CLEC4A3 contains 1 C-type lectin domain and belongs to the C-type lectin-like domain-containing (CLEC) family. Lectins are proteins that are able to recognize and bind with specific carbohydrate molecules. C-type lectins are an important group of proteins found in the immune system of animals. These lectins are named C-type because of their calcium dependent carbohydrate recognition domain (CRD). In the immune system, C-type lectins act as recognition molecules by binding to foreign microorganisms. They also promote the movement and selective adhesion of white blood cells.

The C-type lectin has a three-dimensional fold, the CRD, in which calcium ions contribute to the lectin's ability to recognize and bind carbohydrates. In the immune system, carbohydrate recognition contributes to the ability of immune cells to move from one area of the body to another. It also allows immune cells to identify and discriminate between proteins that belong to the host and those that belong to foreign organisms. There are a number of different C-type lectin subfamilies, including collectins, selectins, proteoglycans, and lymphocyte lectins.

References

Gibbs RA. et al., 2004, Nature. 428: 493-521.
Carninci P. et al., 1999, Methods Enzymol. 303: 19-44.
Shibata K. et al., 2000, Genome Res. 10: 1757-71.

CLEC4A3 related areas, pathways, and other information