Rat CD48 / BCM1 / SLAMF2 Protein (His Tag)

Sino Biological Inc. liefert Rat CD48 / BCM1 / SLAMF2 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Rat CD48 / BCM1 / SLAMF2 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/CD48-BCM1-SLAMF2-Protein-g-9954.html

Produkt-Information von CD48 / BCM1 / SLAMF2 Protein

QC Testing von CD48 / BCM1 / SLAMF2 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: CD48 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Phe 23
Molecular Mass	The recombinant rat CD48 comprises 205 amino acids and predicts a molecular mass of 23.9 kDa. The apparent molecular mass of  the recombinant protein is approximately 38-43 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von CD48 / BCM1 / SLAMF2 Protein

Verwandte Produkte & Themen von CD48 / BCM1 / SLAMF2 Protein

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hematopoietic Stem Cell Marker>>CD48/SLAMF2

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>CD48/SLAMF2

Immunology>>Innate Immunity>>Natural Killer Cell (NK Cell)>>CD48/SLAMF2

Immunology>>Cluster of Differentiation>>Hematopoietic Stem Cell CD Marker>>CD48/SLAMF2

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD48/SLAMF2

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells>>CD48/SLAMF2

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Other>>CD48/SLAMF2

Beschreibung von CD48 / BCM1 / SLAMF2 Protein

CD48, also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD48 is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 has a striking array of biological functions, among them adhesion, pathogen recognition, cellular activation, and cytokine regulation. CD48 performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses. In rodents, CD48 is the ligand for CD2 whereas in humans, CD58 is the ligand for CD2. CD48 has a high degree of sequence homology to CD58 (LFA-3), and Mouse CD48 shares approximately 50% aa sequence identity with human CD48.

References

1. Wong YW. et al., 1990, J Exp Med. 171: 2115-30.
2. Ianelli CJ. et al., 1997, J Immunol. 159 (8): 3910-20.
3. Ianelli CJ. et al., 1998, J Biol Chem. 273: 23367-75.
4. Loertscher, R. et al., 2002, Transpl Immunol. 9: 93-6.
5. Assarsson E. et al., 2005, J Immunol. 175: 2045-9.
6. Bhat R. et al., 2006, J Leukocyte Biol. 79: 417-24.
7. Munitz A. et al., 2007, Recent Pat Inflamm Allergy Drug Discov. 1 (1): 9-12.