PPIL2 (aa 280-457) Protein (His Tag)

11.04.2013

Sino Biological Inc. liefert PPIL2 (aa 280-457) Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über PPIL2 (aa 280-457) Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/PPIL2-Protein-Antibody-a-5767.html

Produkt-Information von PPIL2 Protein

Synonym	PPIL2
Protein Construction	A DNA sequence encoding the mature form of human PPIL2 (Q13356-2) (Gly280-Pro457) was expressed with a polyhistide tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von PPIL2 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: PPIL2 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human PPIL2 consists of 193 amino acids and predicts a molecular mass of 21.9 KDa. It migrates as an approximately 24 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von PPIL2 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von PPIL2 Protein

PPIL2, is an enzyme which belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

References

Grouse LH. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.
Lennon G. et al., 1997, Genome Res. 6 (9): 791-806.
Payan DG. et al., 1996, Biochem J. 314 (1): 313-9.

PPIL2 related areas, pathways, and other information