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Peroxiredoxin 6 / PRDX6 Antikörper

Produkt-Information Peroxiredoxin 6 / PRDX6 Antikörper

Immunogen

Recombinant Human Peroxiredoxin 6 / PRDX6 protein (Catalog#11257-H07E)

Antibody Type Mouse Monoclonal Antibody ( Mouse mAb Service Platform )

Clone ID

01

Ig Type

Mouse IgG1

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Peroxiredoxin 6 / PRDX6 (rh Peroxiredoxin 6 / PRDX6; Catalog#11257-H07E; P30041; Met 1-Pro 224). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Usage Guide von Peroxiredoxin 6 / PRDX6 Antikörper

Specificity

Human Peroxiredoxin 6 / PRDX6

 

No cross-reactivity in ELISA with

E.coli cell lysate

Direct ELISA This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human PRDX6. The detection limit for Human PRDX6 is approximately 0.078 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Peroxiredoxin 6 / PRDX6 Antikörper

Related Areas:

Enzyme>>Oxidoreductase>>Peroxiredoxin 6/PRDX6

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Peroxiredoxin 6/PRDX6 Human Peroxiredoxin 6 /PRDX6 Protein, Recombinant 11257-H07E
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human Peroxiredoxin 6/PRDX6 ELISA Peroxiredoxin 6 / PRDX6 Antibody 11257-MM01
Human Peroxiredoxin 6/PRDX6 WB, ELISA Peroxiredoxin 6 / PRDX6 Antibody 11257-MM03

Hintergrund von Peroxiredoxin 6 / PRDX6 Antikörper

Peroxiredoxin-6, also known as 1-Cys peroxiredoxin, Acidic calcium-independent phospholipase A2, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, PRDX6 and AOP2, is a cytoplasm protein which belongs to theahpC / TSA family and Rehydrin subfamily. Peroxiredoxin-6 / PRDX6 contains onethioredoxin domain. Peroxiredoxin-6 / PRDX6 is involved in redox regulation of the cell. Peroxiredoxin-6 / PRDX6 can reduce H2O2and short chain organic, fatty acid, and phospholipid hydroperoxides. Peroxiredoxin-6 / PRDX6 may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. The Peroxiredoxins / Prx are a family of 25 kDa peroxidases that can reduce H2O2 using an electron from thioredoxin (Trx) or other substances. The mammalian Peroxiredoxins / Prx family is divided into six groups (PRDX1, PRDX2, PRDX3, PRDX4, PRDX5, PRDX6) on the basis of homology of amino acid sequences. They are located in the cytosol and play a role in the cell signaling system. All six mammalian peroxiredoxins are expressed in the lung. Peroxiredoxins / Prx is overexpressed in breast cancer tissues to a great extent suggesting that Peroxiredoxins / Prx has a proliferative effect and may be related to cancer development or progression.

References

  1. Kang S.W., et al., 1998, J. Biol. Chem. 273: 6303-11.
  2. Chen J.-W., et al., 2000, J. Biol. Chem. 275: 28421-7.
  3. Rush J., et al., 2005, Nat. Biotechnol. 23: 94-101.
  4. Noh,D.Y. et al., 2001, Anticancer Res. 21 (3B): 2085-90.
  5. Schremmer,B. et al., 2007, Subcell Biochem. 44: 317-44.

Sino Biological Inc. liefert Peroxiredoxin 6 / PRDX6 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Peroxiredoxin 6 / PRDX6 Antikörper lesen Sie bitte: http://www.sinobiological.com/Peroxiredoxin-6-PRDX6-Antibody-g-9505.html

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