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GM-CSF / CSF2 Antikörper

Produkt-Information von GM-CSF / CSF2 Antikörper

Immunogen

Recombinant Human GM-CSF / CSF2 protein (Catalog#10015-H07H)

Antibody Type Mouse Monoclonal Antibody ( Mouse mAb Service Platform )

Clone ID

06

Ig Type

Mouse IgG1

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GM-CSF / CSF2 (rh GM-CSF / CSF2; Catalog#10015-H07H; NP_000749.2; Ala 18-Glu 144). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Usage Guide von GM-CSF / CSF2 Antikörper

Specificity

Human GM-CSF / CSF2

 

No cross-reactivity in ELISA with

Human cell lysate (293 cell line)

Western blot This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human GM-CSF in WB under non-reducing conditions and reducing conditions is not recommended.
Direct ELISA This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human GM-CSF. The detection limit for Human GM-CSF is approximately 0.16 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von GM-CSF / CSF2 Antikörper

Related Areas:

Cancer>>Growth Factor & Receptor>>CSF & Receptor>>GM-CSF/CSF2

Immunology>>Adaptive Immunity>>T Cell>>Helper T Cell>>GM-CSF/CSF2

Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>IL-6 Family Signaling Related Molecules>>GM-CSF/CSF2

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
GM-CSF/CSF2 Human GM-CSF/CSF2/Fc Protein, Recombinant 10015-H01H
GM-CSF/CSF2 Human GM-CSF / CSF2 Protein, Recombinant 10015-H07H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human GM-CSF/CSF2 WB, ELISA GM-CSF / CSF2 Antibody 10015-MM06

Hintergrund von GM-CSF / CSF2 Antikörper

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine initially characterized by its ability to induce colonies of granulocytes and macrophages from myeloid progenitor cells. GM-CSF is secreted by a variety of cell types including macrophages, T cells, mast cells, endothelial cells and fibroblasts. This cytokine has a central role in governing the proliferation, maturation, differentiation and function of granulocyte and macrophage lineage populations, as well as the migration of endothelial cells. The active form of the protein is found extracellularly as a homodimer, and the encoding gene is localized to a related gene cluster at chromosome region 5q31 which is known to be associated with 5q-syndrome and acute myelogenous leukemia. As a part of the immune/inflammatory cascade, GM-CSF promotes Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity, and thus worthy of consideration for therapeutic target.

References

  1. Frolova, E.I. et al., 1991, Proc. Natl. Acad. Sci. U.S.A. 88: 4821-4824.
  2. Hamilton J.A. et al., 2002, Trends Immunol. 23: 403-408.
  3. Ebner, K. et al., 2003, Blood, 102: 192-199.
  4. Kato,T. et al., 2008, J. Interferon Cytokine Res. 28: 235-243.
  5. Volmar, C.H. et al., 2008, Cytokine. 42: 336-344.

Sino Biological Inc. liefert GM-CSF / CSF2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über GM-CSF / CSF2 Antikörper lesen Sie bitte: http://www.sinobiological.com/GM-CSF-CSF2-Antibody-g-9504.html

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