Mouse KLK11 / Kallikrein-11 Protein (His Tag)

02.05.2012

Produkt-Information von KLK11 / Kallikrein-11 Protein

Synonym	2310015I08Rik, Prss20, TLSP
Protein Construction	A DNA sequence encoding the mouse KLK11 isoform 2 (Q9QYN3) (Met 1-Asn 276), was fused with a C-terminal polyhistidine tag.
Source	Mouse
Expression Host	Human Cells

QC Testing von KLK11 / Kallikrein-11 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: KLK11 / Kallikrein-11 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Glu 45
Molecular Mass	The secreted recombinant mouse KLK11 (pro form) comprises 243 amino acids and has a calculated molecular mass of 27.3 kDa. The apparent molecular mass of rmKLK11 is approximately 38-42 kDa in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from 0.2μm filtered solution of PBS, pH7.4 Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von KLK11 / Kallikrein-11 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Verwandte Produkte & Themen von KLK11 / Kallikrein-11 Protein

Related Areas:

Enzyme>>Protease & Regulator>>Serine Protease & Regulator>>Kallikrein>>KLK11/Kallikrein 11

Cancer>>Angiogenesis>>Kallikrein>>KLK11/Kallikrein 11

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
KLK11/Kallikrein 11	Human	KLK11/Kallikrein 11 Protein, Recombinant	10767-H08H
KLK11/Kallikrein 11	Mouse	KLK11 / Kallikrein-11 Protein, Recombinant	50919-M08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human KLK11/Kallikrein 11	WB, ELISA	Rabbit Monoclonal Antibody	10767-R121
Human KLK11/Kallikrein 11	WB, ELISA	Rabbit Polyclonal Antibody	10767-RP01
Human KLK11/Kallikrein 11	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10767-RP02
Human KLK11/Kallikrein 11	WB, ELISA	KLK11 / Kallikrein 11 Antibody	10767-MM05

Beschreibung von KLK11 / Kallikrein-11 Protein

kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease and PRSS20, is a member of human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiological functions, which is implicated in carcinogenesis and some with potential that serving as novel biomarkers for ovarian and prostate cancer and other diseases. The KLK11 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Two alternatively spliced forms exist, resulting in 250 (isoform 1) and 282 (isoform 2) amino acid sequences. Isoform 2 is identical to isoform 1, except for an inserted 32 amino acid segment. Isoform 1 is predominantly expressed in brain whereas isoform 2 is preferentially expressed in prostate.

References

Yoshida S. et al., 1998, Biochim Biophys Acta. 1399: 225-8.
Yousef GM. et al., 2000,Genomics. 63: 88-96.
Mitsui S. et al., 2000, Biochem Biophys Res Commun. 272: 205-11.
Gan L. et al., 2000, Gene. 257: 119-30.
Yousef GM. et al., 2001, Endocrine Rev. 22: 184-204.
Kong WJ. et al., 2006, J Mol Med Jan. 84 (1): 29-36.

Sino Biological Inc. liefert Mouse KLK11 / Kallikrein-11 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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