Mouse IL6 / Interleukin-6 Protein (Native)

Sino Biological Inc. liefert Mouse IL6 / Interleukin-6 Protein (Native) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Mouse IL6 / Interleukin-6 Protein (Native) lesen Sie bitte: http://www.sinobiological.com/IL6-Interleukin-6-Protein-g-10267.html

Produkt-Information von IL6 / Interleukin-6 Protein

QC Testing von IL6 / Interleukin-6 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: IL6 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met
Molecular Mass	The recombinant mouse IL6 consists of  188 amino acids and predicts a molecular mass of 21.9 KDa. It migrates as an approximately 22 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von IL6 / Interleukin-6 Protein

Verwandte Produkte & Themen von IL6 / Interleukin-6 Protein

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL-6

Cancer>>Cancer Biomarkers>>IL-6

Immunology>>Cytokine & Receptor>>Interleukin & Receptor >>IL-6 Family & Receptor>>IL-6

Beschreibung von IL6 / Interleukin-6 Protein

Interleukin 6 (IL-6, IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation of various tissues, and is known particularly for its role in the immune response and acute phase reactions. IL-6/IL6 is a cytokine with a wide variety of biological functions and belongs to the IL-6 superfamily. IL-6/IL6 is a potent inducer of the acute phase response and plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. IL-6/IL6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. The role of IL-6 as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1Ra and IL-10. IL-6/IL6 is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6/IL6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Inhibitors of IL-6 are used to treat postmenopausal osteoporosis. IL-6/IL6 is thought to be a reason why obese individuals have higher endogeneous levels of CRP. Intranasally administered IL-6 was shown to improve sleep-associated consolidation of emotional memories.

References

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