Mouse IL17BR / IL17RB / IL-17 Receptor B Protein (His Tag)

27.04.2013

Sino Biological Inc. liefert Mouse IL17BR / IL17RB / IL-17 Receptor B Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Mouse IL17BR / IL17RB / IL-17 Receptor B Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/IL-17RB-IL-17BR-Protein-a-2492.html

Produkt-Information von IL17BR / IL17RB / IL-17 Receptor B Protein

Synonym	IL17BR, Evi27, Il17br
Protein Construction	A DNA sequence encoding the mouse IL17BR (Q9JIP3-1) (Met1-Gly286) was expressed with a C-terminal polyhistidine tag.
Source	Mouse
Expression Host	Human Cells

QC Testing von IL17BR / IL17RB / IL-17 Receptor B Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: IL17BR protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Arg18
Molecular Mass	The recombinant mouse IL17BR comprises 280 amino acids and has a predicted molecular mass of 31.3 kDa. The apparent molecular mass of the protein is approximately 42 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von IL17BR / IL17RB / IL-17 Receptor B Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von IL17BR / IL17RB / IL-17 Receptor B Protein

Interleukin-17 receptor B, also known as IL-17 receptor B, IL-17RB, Cytokine receptor-like 4, IL-17 receptor homolog 1, Interleukin-17B receptor, IL-17B receptor, IL17RB and CRL4, is a secreted and single-pass type I membrane protein which contains one SEFIR domain. IL-17B receptor / IL17RB is expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines. IL-17B receptor / IL17RB is a receptor for the proinflammatory cytokines IL17B and IL17E. IL-17B receptor / IL17RB does not bind to IL17 and IL17C. IL-17B receptor / IL17RB may play a role in controlling the growth and / or differentiation of hematopoietic cells. IL-17B receptor / IL17RB has also been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E.

References

Shi Y. et al., 2000, J Biol Chem. 275 (25): 19167-76.
Tian E. et al., 2000, Oncogene. 19: 2098-109.
Matsumoto Y. et al., 2011, Allergol Int. 60 (1): 87-92.
Hunninghake GM. et al., 2011, BMC Pulm Med. 11: 17.