Mouse CREG / CREG1 Protein (His Tag)

15.04.2013

Sino Biological Inc. liefert Mouse CREG / CREG1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Mouse CREG / CREG1 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/CREG1-Protein-a-5761.html

Produkt-Information von CREG / CREG1 Protein

Synonym	CREG, Creg1
Protein Construction	A DNA sequence encoding the mouse CREG (O88668) (Met1-Gln220) was expressed with a C-terminal polyhistidine tag.
Source	Mouse
Expression Host	Human Cells

QC Testing von CREG / CREG1 Protein

Purity	>95% as determined by SDS-PAGE	SDS-PAGE: CREG protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Arg 32
Molecular Mass	The recombinant mouse CREG comprises 200 amino acids and has a predicted molecular mass of 22.9 kDa. The apparent molecular mass of the protein is approximately 28-32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von CREG / CREG1 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von CREG / CREG1 Protein

CREG1 belongs to the CREG family. It is a adenovirus E1A protein which both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. Thus it may contribute to the transcriptional control of cell growth and differentiation. The transcriptional control activity of cell growth requires interaction with IGF2R. CREG1 also antagonizes transcriptional activation and cellular transformation by E1A. It shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. CREG1 gene may contribute to the transcriptional control of cell growth and differentiation.

References

Veal E. et al., 2000, Oncogene. 19 (17): 2120-8.
Wen SJ. et al., 2003, Hypertens Res. 25 (4): 647-52.
Grouse LH. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.

CREG1 related areas, pathways, and other information