LMAN2L Protein (His Tag)

26.11.2012

Sino Biological Inc. liefert LMAN2L Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über LMAN2L Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/LMAN2L-Protein-g-9913.html

Produkt-Information von LMAN2L Protein

Synonym	LMAN2L, VIPL
Protein Construction	A DNA sequence encoding the human LMAN2L (Q9H0V9-1) (Met1-Ala304) was expressed with a polyhistidine tag at the C-terminus.
Source	Human
Expression Host	Human Cells

LMAN2L Protein QC Testing

Purity	> 85% as determined by SDS-PAGE	SDS-PAGE: LMAN2L protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Gly 45
Molecular Mass	The recombinant human LMAN2L consists of 271 amino acids and predicts a molecular mass of 31.4 KDa. It migrates as an approximately 32 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von LMAN2L Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von LMAN2L Protein

LMAN2L contains 1 L-type lectin-like domain. LMAN2L gene contains 15 distinct gt-ag introns and may be modulated by acetylation; phosphorylation, as detailed at PhosphoSite. Alternative splicing produces 2 isoforms of the human protein. LMAN2L localize in various compartments. It is highly expressed in skeletal muscle and kidney, and its intermediate expression levels in heart, liver and placenta, low levels in brain, thymus, spleen, small intestine and lung. LMAN2L may be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. It also may function as a regulator of ERGIC-53.

References

Hartley JL. et al., 2001, Genome Res. 10 (11): 1788-95.
Suzuki Y. et al., 1997, Gene. 200 (1-2) :149-56.
Maruyama K. et al., 1994, Gene. 138 (1-2): 171-4.