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Lactotransferrin / LTF Antikörper (Antigen Affinität reinigt)

Proudkt-Information von Lactotransferrin / LTF Antikörper

Immunogen

Recombinant Human Lactotransferrin / LTF protein (Catalog#50036-M08H)

Antibody Type Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

Produced in rabbits immunized with purified, recombinant Human Lactotransferrin / LTF (rh Lactotransferrin / LTF; Catalog#11096-H08H; P02788; Met 1-Lys 710). Lactotransferrin / LTF specific IgG was purified by Human Lactotransferrin / LTF affinity chromatography.

Usage Guide von Lactotransferrin / LTF Antikörper

Specificity

Human Lactotransferrin / LTF

Immunochemistry

IHC-P: 0.1-2 μg/mL

LTF-placenta immunohistochemistry    LTF-spleen immunohistochemistry

Immunochemical staining of human LTF in human placenta with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). The image showing positive staining of leukocytes. Immunochemical staining of human LTF in human spleen with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Western blot This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human LTF in WB. Using a DAB detection system, the detection limit for Human LTF is approximately 0.5 ng/lane under non-reducing conditions. Use of this antibody under reducing conditions is not recommended.
Direct ELISA This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human LTF. The detection limit for Human LTF is approximately 0.039 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von Lactotransferrin / LTF Antikörper

Related Areas:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
LTF Human Lactotransferrin/LTF Protein, Recombinant 11096-H08H
LTF Mouse LTF / Lactoferrin Protein, Recombinant 50750-M08H
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human LTF WB, ELISA, IHC-P Lactotransferrin / LTF Antibody (Antigen Affinity Purified) 11096-RP02

Hintergrund von Lactotransferrin / LTF Antikörper

Lactotransferrin, also known as Lactoferrin, Talalactoferrin and LTF, is a secreted protein which belongs to thetransferrin family. Transferrins are iron binding transport proteins which can bind two Fe3+ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and lactoferroxin C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. Lactoferrin / LTF is a globular glycoprotein that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin / LTF is also present in secondary granules of PMN and is secreted by some acinar cells. Lactoferrin / LTF can be purified from milk or produced recombinantly. Human colostrum has the highest concentration, followed by human milk, then cow milk. Lactoferrin / LTF is one of the components of the immune system of the body; it has antimicrobial activity (bacteriocide, fungicide) and is part of the innate defense, mainly at mucoses. In particular, lactoferrin provides antibacterial activity to human infants. Lactoferrin interacts with DNA and RNA, polysaccharides and heparin, and shows some of its biological functions in complexes with these ligands.

References

  1. Sanchez L, et al.,1992, Arch. Dis. Child. 67 (5): 657-61.
  2. Wakabayashi H, et al., 2000, J. Antimicrob. Chemother. 46 (4): 595-602.
  3. Nozaki A, et al., 2003,J. Biol. Chem. 278 (12): 10162-73.
  4. Azzam HS, et al., 2007, Liver Int. 27 (1): 17-25.

Sino Biological Inc. liefert Lactotransferrin / LTF Antikörper (Antigen Affinität reinigt) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Lactotransferrin / LTF Antikörper (Antigen Affinität reinigt) lesen Sie bitte: http://www.sinobiological.com/Lactotransferrin-LTF-Antibody-g-9110.html

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