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IGFBP7 Antikörper (Antigen Affinity Purified)

Produkt-Information von IGFBP7 Antikörper

Immunogen

Recombinant Human IGFBP7 protein (Catalog#13100-H08H)

Antibody Type Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

Produced in rabbits immunized with purified, recombinant Human IGFBP7 (rh IGFBP7; Catalog#13100-H08H; Q16270; Met 1-Leu 282). IGFBP7 specific IgG was purified by Human IGFBP7 affinity chromatography.

Usage Guide von IGFBP7 Antikörper

Specificity

Human IGFBP7

Immunochemistry

IHC-P: 0.1-2 μg/mL

IGFBP7-pancreas immunohistochemistry    

Immunochemical staining of human IGFBP7 in human pancreas with rabbit polyclonal antibody (1 μg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to pancreatic islet.  
Direct ELISA This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human IGFBP7. The detection limit for Human IGFBP7 is approximately 0.039 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von IGFBP7 Antikörper

Related Areas:

Cancer>>Growth Factor & Receptor>>IGF System>>IGFBP7

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
IGFBP7 Human IGFBP7 Protein, Recombinant 13100-H02H
IGFBP7 Human IGFBP7 Protein, Recombinant 13100-H08H
IGFBP7 Human IGFBP7 / IBP-7 Protein, Recombinant 13100-H07H
Antibodies:
Molecule SApplication Description //For Detailed Info. and Price------CLICK! Cat. No
Human IGFBP7 ELISA, IHC-P IGFBP7 Antibody (Antigen Affinity Purified) 13100-RP02

Hintergrund von IGFBP7 Antikörper

Insulin-like growth factor-binding protein 7, also known as IGF-binding protein 7, IBP-7, IGFBP-7, IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, Prostacyclin-stimulating factor, Tumor-derived adhesion factor TAF and IGFBP7, is a secreted protein involved in several cellular processes, including proliferation, senescence and apoptosis. Loss of IGFBP7 expression is a critical step in the development of human tumors, including melanoma and colon cancer. IGFBP7 contains oneIg-like C2-type (immunoglobulin-like) domain, oneIGFBP N-terminal domain and one Kazal-like domain. IGFBP7 binds IGF-I and IGF-II with a relatively low affinity. IGFBP7 stimulates prostacyclin (PGI2) production. It also stimulates cell adhesion. The major function of the IGFBP7 protein is in the regulation of availability ofInsulin like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity. It also stimulates cell adhesion. IGFBP7 protein is implicated in some cancers.

References

  1. Akaogi K. et al.,1994, Biochem Biophys Res Commun. 198: 1046-53.
  2. Oh Y. et al., 1996, J Biol Chem. 271: 30322-30325.
  3. Wilson EM. et al., 2001, J Clin Endocrinol Metab. 86: 4504-4511.
  4. Sanjida Ahmed., et al., 2006, FEBS Journal.273 (3): 615-27.
  5. Gommans WM., et al., 2008, RNA. 14: 2074-2085.
  6. Vizioli MG. et al., 2010, Oncogene. 29 (26): 3835-44.

Sino Biological Inc. liefert IGFBP7 Antikörper (Antigen Affinity Purified) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über IGFBP7 Antikörper (Antigen Affinity Purified) lesen Sie bitte: http://www.sinobiological.com/IGFBP7-Antibody-g-9362.html

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