HNRNPR / HNRNP-R / HNRNP R Protein (GST Tag)

06.03.2013

Sino Biological Inc. liefert HNRNPR / HNRNP-R / HNRNP R Protein (GST Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über HNRNPR / HNRNP-R / HNRNP R Protein (GST Tag) lesen Sie bitte: http://www.sinobiological.com/HNRNPR-HNRNP-R-HNRNP-R-Protein-g-10546.html

Produkt-Information von HNRNPR / HNRNP-R / HNRNP R Protein

Synonym	HNRNPR, HNRPR
Protein Construction	A DNA sequence encoding the human HNRNPR (O43390-2) (Ala2-Lys636) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Source	Human
Expression Host	Baculovirus-Insect cells

QC Testing von HNRNPR / HNRNP-R / HNRNP R Protein

Purity	> 90 % as determined by SDS-PAGE	SDS-PAGE: HNRNPR protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met
Molecular Mass	The recombinant human HNRNPR /GST chimera consists of 872 amino acids and has a calculated molecular mass of 98.9 kDa. The recombinant protein migrates as an approximately 114 kDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, 0.5mM GSH, pH 8.5, 3mM DTT, 10% glycerol. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von HNRNPR / HNRNP-R / HNRNP R Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von HNRNPR / HNRNP-R / HNRNP R Protein

HNRNP R, also known as HNRNPR, is a component of ribonucleosomes, which are complexes of at least 20 other different heterogenious nuclear ribonucleoproteins (hnRNP). HNRNP R gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). HnRNPs complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. The hnRNP proteins have distinct nucleic acid binding properties. HNRNP R has three repeats of quasi-RRM domains that bind to RNAs and also contains a nuclear localization motif.

References

Rossoll. et al., 2002, Hum Mol Genet. 11 (1): 93-105.
Mourelatos Z. et al., 2001, EMBO J. 20 (19): 5443-52.
Hassfeld W. et al., 1998, Nucleic acids Res. 26 (2): 439-45.
HNRNP R (HNRNPR) related areas, pathways, and other information