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HAGH / GLO2 / Glyoxalase II Antikörper (Antigen Affinität reinigt)

Produkt-Information von HAGH / GLO2 / Glyoxalase II Antikörper

Immunogen

Recombinant Human HAGH / GLO2 / Glyoxalase II protein (Catalog#12146-H08E)

Antibody Type Rabbit Polyclonal Antibody ( Antibody Purification Platform )
Ig Type

Rabbit IgG

Formulation 0.2 μm filtered solution in PBS with 5% trehalose
Preparation

Produced in rabbits immunized with purified, recombinant Human HAGH / GLO2 / Glyoxalase II (rh HAGH / GLO2 / Glyoxalase II; Catalog#12146-H08E; Q16775-2; Met 1-Asp 260). HAGH / GLO2 / Glyoxalase II specific IgG was purified by Human HAGH / GLO2 / Glyoxalase II affinity chromatography.

Usage Guide von HAGH / GLO2 / Glyoxalase II Antikörper

Specificity

Human HAGH / GLO2 / Glyoxalase II

Immunochemistry

IHC-P: 0.1-2 μg/mL

HAGH-kidney immunohistochemistry    HAGH-liver immunohistochemistry

Immunochemical staining of human HAGH in human kidney with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human HAGH in human liver with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Western blot This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human HAGH in WB. Using a DAB detection system, the detection limit for Human HAGH is approximately 0.5 ng/lane under non-reducing conditions and reducing conditions.
Direct ELISA This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human HAGH. The detection limit for Human HAGH is approximately 0.00245 ng/well.
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von HAGH / GLO2 / Glyoxalase II Antikörper

Related Areas:

Enzyme>>Other>>HAGH/GLO2/Glyoxalase II

Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
HAGH/GLO2 Human HAGH/GLO2/Glyoxalase II Protein, Recombinant 12146-H08E
Antibodies:
Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human HAGH/GLO2 ELISA, IHC-P HAGH / GLO2 / Glyoxalase II Antibody (Antigen Affinity Purified) 12146-RP02

Hintergrund von HAGH / GLO2 / Glyoxalase II Antikörper

Hydroxyacylglutathione hydrolase, also known as Glyoxalase II, HAGH and GLO2, is a mitochondrion matrix and cytoplasm protein which belongs to themetallo-beta-lactamase superfamily and Glyoxalase II family. Glyoxalase II (HAGH / GLO2) is a thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. The glyoxalase II (HAGH / GLO2) activity in normal human muscle was very low, and the activity was unaltered in muscle of patients with Duchenne and other major forms of muscular dystrophies and spinal muscular atrophy. The selective decrease of glyoxalase I activity in recessively inherited muscular dystrophies may have some relevance to some phases of these disease processes.

References

  1. Daniels R.J., et al., 2001, Hum. Mol. Genet. 10: 339-352.
  2. Ota T., et al.,2004, Nat. Genet. 36: 40-45.
  3. Cordell P.A., et al., 2004, J. Biol. Chem. 279: 28653-28661.

Sino Biological Inc. liefert HAGH / GLO2 / Glyoxalase II Antikörper (Antigen Affinität reinigt) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über HAGH / GLO2 / Glyoxalase II Antikörper (Antigen Affinität reinigt) lesen Sie bitte: http://www.sinobiological.com/HAGH-GLO2-Glyoxalase-II-Antibody-g-9112.html

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