Glutaredoxin / GRX1 / GLRX Protein (His Tag)

28.05.2013

Sino Biological Inc. liefert Glutaredoxin / GRX1 / GLRX Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Glutaredoxin / GRX1 / GLRX Protein (His Tag)) lesen Sie bitte:http://www.sinobiological.com/Glutaredoxin-1-GRX1-GLRX-Protein-Antibody-a-6217.html

Produkt-Information von Glutaredoxin / GRX1 / GLRX Protein

Synonym	GLRX, GRX
Protein Construction	A DNA sequence encoding the human GLRX (P35754)(Met1-Gln106) was expressed with a polyhistidine tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von Glutaredoxin / GRX1 / GLRX Protein

Purity	> 85 % as determined by SDS-PAGE	SDS-PAGE: GLRX protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human GLRX consists of 121 amino acids and predicts a molecular mass of 13.6 KDa. It migrates as an approximately 12 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile 50mM Tirs, 10% Glycerol, 1mM DTT, pH 8.0. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von Glutaredoxin / GRX1 / GLRX Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von Glutaredoxin / GRX1 / GLRX Protein

Glutaredoxin-1, also known as GRX1 and GLRX, belongs to the glutaredoxin family. Glutaredoxins are small redox enzymes that use glutathione as a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically by glutathione. Glutaredoxin-1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. Glutaredoxin-1 exists in either a reduced or an oxidized form. Glutaredoxins function as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.

References

Holmgren A. et al., 1988, FEMS Microbiol Rev. 4 (4): 271-97.
Holmgren A. 1988, Biochem Soc Trans. 16 (2): 95-6.
Holmgren A. 1989, J Biol Chem. 264 (24): 13963-6.