VAMP3 / Cellubrevin Protein (His Tag)

28.05.2013

Sino Biological Inc. liefert VAMP3 / Cellubrevin Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über VAMP3 / Cellubrevin Protein (His Tag) lesen Sie bitte:http://www.sinobiological.com/VAMP3-Cellubrevin-Protein-Antibody-a-6210.html

Produkt-Information von VAMP3 / Cellubrevin Protein

Synonym	VAMP3, SYB3
Protein Construction	A DNA sequence encoding the human VAMP3 (Q15836) (Met1-Lys77) was expressed with a polyhistidine tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von VAMP3 / Cellubrevin Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: VAMP3 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human VAMP3 consists of 92 amino acids and predicts a molecular mass of 10.6 KDa. It migrates as an approximately 11 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, 10% Glycerol, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von VAMP3 / Cellubrevin Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von VAMP3 / Cellubrevin Protein

VAMP3, also known as cellubrevin, is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Because of VAMP3 gene's high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, VAMP3 was shown to be the human equivalent of the rodent cellubrevin. In platelets VAMP3 resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.

References

Bernstein AM. et al., 1999, Blood. 93 (2): 571-9.
Annaert WG. et al., 1997, J Cell Biol. 139 (6): 1397-410.
Hager HA. et al., 2010, EMBO J. 29 (3): 532-45.