GATE-16 / GABARAPL2 Protein (His Tag)

25.04.2013

Sino Biological Inc. liefert GATE-16 / GABARAPL2 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über GATE-16 / GABARAPL2 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/GATE-16-GABARAPL2-Protein-Antibody-a-5856.html

Produkt-Information von GATE-16 / GABARAPL2 Protein

Synonym	GABARAPL2, FLC3A, GEF2
Protein Construction	A DNA sequence encoding the mature form of human GABARAPL2 (P60520) (Met1-Phe117) was expressed with a polyhistide tag at the N-terminus.
Source	Human
Expression Host	Human Cell

QC Testing von GATE-16 / GABARAPL2 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: GATE-16 protein
Endotoxin	<1.0 EU per μg protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human GABARAPL2 consists of 132 amino acids and predicts a molecular mass of 15.5 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von GATE-16 / GABARAPL2 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von GATE-16 / GABARAPL2 Protein

GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.

References

Ewing. et al., 2007, Mol Syst Biol. 3(1):89.
Okazaki N. et al., 2000, Brain Res Mol Brain Res. 85 (1-2): 1-12.
Xin Y. et al., 2001, Genomics. 74 (3): 408-13.

GATE-16 (GABARAPL2) related areas, pathways, and other information