FUCA1 Protein (His Tag)

Sino Biological Inc. liefert FUCA1 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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Produkt-Information von FUCA1 Protein

QC Testing von FUCA1 Protein

Purity	> 95% as determined by SDS-PAGE	SDS-PAGE: FUCA1 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Gln 32
Molecular Mass	The recombinant human FUCA1 consists of  446 amino acids and predicts a molecular mass of 51.9 KDa. It migrates as an approximately 57 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von FUCA1 Protein

Verwandte Produkte & Themen von FUCA1 Protein

Beschreibung von FUCA1 Protein

FUCA1 is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in FUCA1 gene can cause fucosidosis. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective FUCA1 with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form; coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form; and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.

References

1. Yang M. et al., 1993, Biochem Biophys Res Commun. 189 (2): 1063-8.
2. Fukushima H. et al., 1991, J Inherit Metab Dis. 13 (5): 761-5.
3. Kretz KA. et al., 1990, J Mol Neurosci. 1 (3): 177-80.

FUCA1 related areas, pathways, and other information