EZR / VIL2 / Ezrin Protein (His Tag)

26.11.2012

Sino Biological Inc. liefert EZR / VIL2 / Ezrin Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über EZR / VIL2 / Ezrin Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/EZR-VIL2-Ezrin-Protein-g-9909.html

Produkt-Information von EZR / VIL2 / Ezrin Protein

Synonym	EZR, VIL2
Protein Construction	A DNA sequence encoding the mature form of human EZR(P15311) (Pro2-Leu586) was expressed with a polyhistide tag at the N-terminus.
Source	Human
Expression Host	E.coli

QC Testing von EZR / VIL2 / Ezrin Protein

Purity	> 60% as determined by SDS-PAGE	SDS-PAGE: EZR protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	His
Molecular Mass	The recombinant human EZR consists of 601 amino acids and predicts a molecular mass of 71.2 KDa. It migrates as an approximately 82 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS 100mM Arg 10% glycerol, 0.1%Twen 20, pH 7.5. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von EZR / VIL2 / Ezrin Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von EZR / VIL2 / Ezrin Protein

VIL2, also known as villin-2, is a member of the ERM protein family. It contains 1 FERM domain and is expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. VIL2/Ezrin/EZR functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, VIL2/Ezrin/EZR serves as an intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization. It interacts with MPP5 and SLC9A3R2. It is found VIL2/Ezrin/EZR form a complex with PODXL and SLC9A3R2. It also interacts with MCC, PLEKHG6, PODXL, SCYL3/PACE1, SLC9A3R1 and TMEM8B.

References

Gr?nholm M. et al., 1999, J Cell Sci. 112 (6): 895-904.
Sitaraman. et al., 2002, J Biol Chem. 277 (36): 33188-95.
Gould KL. et al., 1989, EMBO J. 8 (13): 4133-42.

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
VIL2 / villin-2	Human	EZR / VIL2 / Ezrin Protein, Recombinant	12858-H07E