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FCER1A / FcERI Protein (His Tag)

Sino Biological Inc. liefert FCER1A / FcERI Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über FCER1A / FcERI Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/FCER1A-FcERI-Protein-g-9910.html

Produkt-Information von FCER1A / FcERI Protein

Synonym FCER1A, FCE1A
Protein Construction

A DNA sequence encoding the human FCER1A (P12319) (Met1-Gln205) was expressed with a polyhistidine tag at the C-terminus.

Source Human
Expression Host Human Cells

QC Testing von FCER1A / FcERI Protein

Purity > 95% as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

FCER1A protein

Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Stability Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal Val 26
Molecular Mass

The recombinant human FCER1A consists of  191 amino acids and predicts a molecular mass of 24.5 KDa. It migrates as an approximately 42-48 KDa band in SDS-PAGE under reducing conditions.

Formulation Lyophilized from sterile PBS, pH 7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von FCER1A / FcERI Protein

Storage Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Verwandte Produkte & Themen von FCER1A / FcERI Protein

Related Areas:
Proteins:
Molecule Species Description //For Detailed Info. and Price------CLICK! Cat No
FcERI / FCER1A Human FCER1A / FcERI Protein, Recombinant 13193-H08H
FcERI / FCER1A Mouse FcERI / FCER1A Protein, Recombinant 50935-M02H
Antibodies:

Beschreibung von FCER1A / FcERI Protein

FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is comprised of an alpha subunit(FcERI), a beta subunit, and two gamma subunits. IgE receptor is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. FcERI is glycosylated. It contains 2 Ig-like (immunoglobulin-like) domains.

References

  1. Shikanai T. et al., 2002, J Appl Physiol. 93 (1): 37-41.
  2. Sada K. et al., 2002, Blood. 100 (6): 2138-44.
  3. Takahashi K. et al., 2003, Mol Immunol. 38 (16-18): 1193-9.
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