EphB6 Antikörper ( FITC )

28.06.2012

Produkt-Information von EphB6 Antikörper

Immunogen	Recombinant Human EphB6 protein (Catalog#10197-H08H)
Reagents	FITC-conjugated mouse monoclonal antibody
Clone ID	05
Ig Type	Mouse IgG2b
Concentration	5 μl/Test, 0.2 mg/ml
Formulation	Aqueous solution containing 0.5% BSA and 0.1% sodium azide
Preparation	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EphB6 (rh EphB6; Catalog#10197-H08H; NP_004436.1; Met 1-Ser 579) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Usage Guide von EphB6 Antikörper

Specificity	Human EphB6
	No cross-reactivity in ELISA with Human EphB4 Human cell lysate (293 cell line)
Flow Cytometry	Flow cytometric analysis of anti-Human EphB6 reactivity on Jurkat cells. Profile of anti-Human EphB6 reactivity on Jurkat cells analyzed by flow cytometry. Flow cytometry was performed on a BD FACSCalibur flow cytometry system Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.
Storage	This antibody is stable for 12 months from date of receipt when stored at 2℃- 8℃. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Verwandte Produkte & Themen von EphB6 Antikörper

Related Areas:

Enzyme>>Protein Kinase>>Receptor Tyrosine Kinase>>EphB6

Neuroscience>>Axon Guidance>>Ephrin & Eph Receptor>>EphB6

Signal Transduction>>Protein Kinase>>Receptor Tyrosine Kinase>>EphB6

Cancer>>Growth Factor & Receptor>>Ephrin & Eph Receptor>>EphB6

Cancer>>Growth Factor & Receptor>>Receptor Tyrosine Kinase>>EphB6

Immunology>>Adaptive Immunity>>Costimulation & Costimulatory Molecule>>EphB6

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
EphB6	Human	EphB6/Fc Protein, Recombinant	10197-H02H
EphB6	Human	EphB6 Protein, Recombinant	10197-H08H
EphB6	Human	EphB6 Protein, Recombinant	10197-HCCH

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human EphB6	FCM	EphB6 Antibody ( FITC )	10197-MM05-F
Human EphB6	WB, ELISA	EphB6 Antibody, Mouse MAb	10197-MM07
Human EphB6	WB, ELISA	EphB6 Antibody, Rabbit PAb	10197-RP01
Human EphB6	WB, ELISA	EphB6 Antibody, Rabbit PAb (Antigen Affinity Purified)	10197-RP02

Hintergrund von EphB6 Antikörper

Ephrins are divided into the ephrin-A (EFNA) class and the ephrin-B (EFNB) class based on their structures and sequence relationships. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family, and EphB6 binding to ephrin-B ligands is a unique member in that its kinase domain contains several alterations in conserved amino acids and is catalytically inactive. It is indicated that activated by an Src family kinase, EphB6 can act as both positive and negative regulators in the process of cell adhesion and migration,The large family of Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly the establishment of regional pattern in the nervous system. Furthermore, the Eph receptors have been suggested to play important roles in tumor formation, prognosis, and possible gene-therapeutic approaches, and the reduction of EphB6 gene expression is associated with the progression of metastatic diseases.

References

Flanagan, J.G. et al., 1998, Annu. Rev. Neurosci. 21: 309-345.
Matsuoka, H. et al., 2005, J. Biol. Chem. 280: 29355-29363.
Holder, N. et al., 1999, Development. 126: 2033-2044.
Cheng, N. et al., 2002, Cytokine. Growth. Factor. Rev. 13: 75-85.
Hafner,C. et al., 2003, Int. J.Oncol. 23: 1553-1559.
Fox, B.P. et al., 2006, Biochem.Biophys.Res.Commun.340: 268-276.

Sino Biological Inc. liefert EphB6 Antikörper ( FITC ) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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