CD95 / APO-1 / TNFRSF6 / FAS Antikörper ( FITC )

28.06.2012

Produkt-Information von CD95 / APO-1 / TNFRSF6 / FAS Antikörper

Immunogen	Recombinant Human CD95 / APO-1 / TNFRSF6 / FAS protein (Catalog#10217-H08H)
Reagents	FITC-conjugated mouse monoclonal antibody
Clone ID	10
Ig Type	Mouse IgG1
Concentration	5 μl/Test, 0.2 mg/ml
Formulation	Aqueous solution containing 0.5% BSA and 0.1% sodium azide
Preparation	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD95 / APO-1 / TNFRSF6 / FAS (rh CD95 / APO-1 / TNFRSF6 / FAS; Catalog#10217-H08H; NP_000034.1; Met 1-Asn 173) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Usage Guide von CD95 / APO-1 / TNFRSF6 / FAS Antikörper

Specificity

Human CD95 / APO-1 / TNFRSF6 / FAS

Flow Cytometry

Flow cytometric analysis of anti-Human FAS (CD95) reactivity on Jurkat cells.

Profile of anti-Human FAS (CD95) reactivity on Jurkat cells analyzed by flow cytometry.

Flow cytometry was performed on a BD FACSCalibur flow cytometry system

Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.

Storage

This antibody is stable for 12 months from date of receipt when stored at 2℃- 8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Verwandte Produkte & Themen von CD95 / APO-1 / TNFRSF6 / FAS Antikörper

CD95 / APO-1 / TNFRSF6 / FAS Antibody Related Areas:

Immunology>>Adaptive Immunity>>T Cell>>Regulatory T Cell>>CD95/APO-1/TNFRSF6

Immunology>>Cytokine & Receptor>>TNF Superfamily>>CD95/APO-1/TNFRSF6

Immunology>>Innate Immunity>>Natural Killer Cell (NK Cell)>>CD95/APO-1/TNFRSF6

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD95/APO-1/TNFRSF6

Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Neutrophils>>CD95/APO-1/TNFRSF6

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Other>>CD95/APO-1/TNFRSF6

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells / Regulatory T Cells>>CD95/APO-1/TNFRSF6

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD95/APO-1/TNFRSF6	Human	CD95/APO-1/TNFRSF6/Fc Protein, Recombinant	10217-H02H
CD95/APO-1/TNFRSF6	Human	CD95/APO-1/TNFRSF6 Protein, Recombinant	10217-H08H
CD95/APO-1/TNFRSF6	Mouse	CD95/APO-1/TNFRSF6 Protein, Recombinant	50027-M08H
CD95/APO-1/TNFRSF6	Rat	CD95/APO-1/TNFRSF6 Protein, Recombinant	80043-R08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb	10217-RP01
Human CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb (Antigen Affinity Purified)	10217-RP02
Mouse CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb	50027-RP01
Mouse CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Rabbit PAb (Antigen Affinity Purified)	50027-RP02
Human CD95/APO-1/TNFRSF6	WB, ELISA	CD95/APO-1/TNFRSF6 Antibody, Mouse MAb	10217-MM04
Human CD95/APO-1/TNFRSF6	FCM	CD95 / APO-1 / TNFRSF6 / FAS Antibody ( FITC )	10217-MM10-F

Hintergrund von CD95 / APO-1 / TNFRSF6 / FAS Antikörper

Fas, also known as APO-1, CD95 and TNFRSF6, is a member of the tumor necrosis factor (TNF) / nerve growth factor (NGF) receptor superfamily. Fas is highly expressed on the surface of a number of cell types including epithelial cells, hepatocytes, activated mature lymphocytes and other tumor cells. This receptor contains a death domain and has been shown to play a central role in the physiological regulation of programmed cell death (PCD, apoptosis) upon ligation of Fas ligand (Fas-L). This Fas receptor has been reported to be involved in the activation of NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and the alternate pathways for CTL-mediated cytotoxicity. Accordingly, this protein is implicated in the pathogenesis of various malignancies and diseases of the immune system. Multiple Fas isoforms are derived from alternative spliced transcript variants, and among which, a soluble form lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoforms.

References

Brunner,T. et al., 1995, Nature. 373: 441-444.
Hirata, H. et al., 1998, J. Exp. Med. 187: 587-600.
Suda, T. et al., 1993, Cell. 75: 1169-1178.
Milhas,D. et al., 2005, J. Biol. Chem. 280:19836-19842.
Cascino, I. et al., 1995, J.Immunol. 154: 2706-2713.
Mary, M. et al., 2001, J. Biol. Chem. 276: 4964-4971.

Sino Biological Inc. liefert CD95 / APO-1 / TNFRSF6 / FAS Antikörper ( FITC ) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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