EPHA3 Protein (His Tag)

01.03.2013

Sino Biological Inc. liefert EPHA3 Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über EPHA3 Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/EPHA3-Protein-g-10535.html

Produkt-Information von EPHA3 Protein

Synonym	EPHA3
Protein Construction	A DNA sequence encoding the human EPHA3 (Met1-Gln541) was expressed with a polyhistidine tag at the C-terminus.
Source	Human
Expression Host	Human Cells

QC Testing von EPHA3 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: EPHA3 protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Glu 21
Molecular Mass	The recombinant human EPHA3 consists of 532 amino acids and predicts a molecular mass of 60.3 KDa. It migrates as an approximately 65-70 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von EPHA3 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von EPHA3 Protein

EPHA3 gene is a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.

References

Holder N. et al., 1999, Development. 126 (10): 2033-44.
Wilkinson DG. 2000, Int Rev Cytol. 196: 177-244.
Xu Q. et al., 2001, Philos Trans R Soc Lond B Biol Sci. 355 (1399): 993-1002.