BLBP / FABP7 Protein (Native)

01.03.2013

Sino Biological Inc. liefert BLBP / FABP7 Protein (Native) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über BLBP / FABP7 Protein (Native) lesen Sie bitte: http://www.sinobiological.com/BLBP-FABP7-Protein-g-10536.html

Produkt-Information von BLBP / FABP7 Protein

Synonym	FABP7, BLBP, FABPB, MRG
Protein Construction	A DNA sequence encoding the mature form of human FABP7 (O15540) (Met1-Ala132) was expressed.
Source	Human
Expression Host	E.coli

QC Testing von BLBP / FABP7 Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: BLBP / FABP7 protein
Endotoxin	Please contact us for more information.
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Met
Molecular Mass	The recombinant human FABP7 consists of 132 amino acids and predicts a molecular mass of 14.9 KDa. It migrates as an approximately 16 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, PH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von BLBP / FABP7 Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschriebung von BLBP / FABP7 Protein

BLBP, also known as FABP7, is a brain fatty acid binding protein which belongs to fatty acid binding proteins (FABPs) family. FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP variation is linked to weak prepulse inhibition(PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.

References

Shi YE. et al., 1997, Cancer Res. 57 (15): 3084-91.
Young JK. et al., 1997, Glia. 16 (3): 218-26.
Xu LZ. et al., 1996, J Biol Chem. 271 (40): 24711-9.