EGFR / HER1 / ErbB1 Antikörper ( FITC )

Produkt-Information von EGFR / HER1 / ErbB1 Antikörper

Usage Guide von EGFR / HER1 / ErbB1 Antikörper

Specificity	Human EGFR / HER1 / ErbB1
Flow Cytometry	Flow cytometric analysis of anti-EGFR reactivity on A431 cells. Profile of anti-EGFR reactivity on A431 cells analyzed by flow cytometry. Flow cytometry was performed on a BD FACSCalibur flow cytometry system Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.
Storage	This antibody is stable for 12 months from date of receipt when stored at 2℃- 8℃. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Verwandte Produkte & Themen von EGFR / HER1 / ErbB1 Antikörper

Hintergrund von EGFR / HER1 / ErbB1 Antikörper

As a member of the epidermal growth factor receptor tyrosine kinases subfamily, EGF R is a type Ⅰ transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR signaling plays a crucial role in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR homo- or hetero- dimerization, initiates subsequent tyrosine autophosphorylation and various downstream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling has been shown to exert actions on carcinogenesis and disease progression, and thus EGFR was proposed as a target for cancer therapy currently.

References

1. Schlessinger, J., 2000, Cell. 103:211-225.
2. Giaccone, G., 2005, Ann. Onc. 16: 538-548.
3. Yarden, Y., 2001, Nat. Rev. Mol. Cell. Biol. 2: 127-137.

Sino Biological Inc. liefert EGFR / HER1 / ErbB1 Antikörper ( FITC ) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über EGFR / HER1 / ErbB1 Antikörper ( FITC ) lesen Sie bitte: http://www.sinobiological.com/EGFR-HER1-ErbB1-Antibody-g-8809.html