CD50 / ICAM-3 Antikörper ( FITC )

16.05.2012

Produkt-Information von ICAM3 / CD50 Antikörper

Immunogen	Recombinant Human ICAM3 / CD50 protein (Catalog#10333-H08H)
Reagents	FITC-conjugated mouse monoclonal antibody
Clone ID	4H6F9B8
Ig Type	Mouse IgG2a
Concentration	5 μl/Test, 0.2 mg/ml
Formulation	Aqueous solution containing 0.5% BSA and 0.1% sodium azide
Preparation	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD50 / ICAM-3 (rh CD50 / ICAM-3; Catalog#10333-H08H; NP_002153.2; Met 1-His 485) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Usage Guide von ICAM3 / CD50 Antikörper

Specificity	Human CD50 / ICAM-3
Flow Cytometry	The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable lymphocytes. Profile of peripheral blood lymphocytes analyzed by flow cytometry. Flow cytometry was performed on a BD FACSCalibur flow cytometry system Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.
Western blot	This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human ICAM3 in WB.
Storage	This antibody is stable for 12 months from date of receipt when stored at 2℃- 8℃. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Verwandte Produkte & Themen von ICAM3 / CD50 Antikörper

ICAM3 / CD50 Antibody Related Areas:

Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>CD50/ICAM-3

Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Adhesion>>CD50/ICAM-3

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD50/ICAM-3	Human	CD50/ICAM-3/Fc Protein, Recombinant	10333-H03H
CD50/ICAM-3	Human	CD50/ICAM-3 Protein, Recombinant	10333-H08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CD50/ICAM-3	WB, FCM	CD50 / ICAM-3 Antibody ( FITC )	10333-MM02-F
Human CD50/ICAM-3	WB, ELISA	CD50/ICAM-3 Antibody, Mouse MAb	10333-MM07
Human CD50/ICAM-3	WB, ELISA	CD50 / ICAM-3 Antibody	10333-RP01
Human CD50/ICAM-3	WB, ELISA	CD50 / ICAM-3 Antibody (Antigen Affinity Purified)	10333-RP02

Hintergrund von ICAM3 / CD50 Antikörper

The protein ICAM3, also known as CD50, is a member of the intercellular adhesion molecule (ICAM) family consisting three members. All ICAM proteins are type I transmembrane glycoproteins, and are ligands for leukocyte function-associated antigen 1 (LFA-1) expressed on the surface of all white blood cells. ICAM-3 comprises of five immunoglobulin-like domains, and binds LFA-1 through its two N-terminal domains. It functions not only as an adhesion molecule, but also as a potent signalling molecule.ICAM3 is constitutively and abundantly expressed by all leucocytes, and thus is the major ligand for LFA-1 in the initiation of primary immune responses. It has been reported that CD50 molecule can play a role in developing functionally mature T lymphocytes and its expression increases during the maturation process of T lymphocytes. In addition, the interactions of ICAM-3 and LFA-1 facilitate HIV-1- induced virological synapse formation between T cells.

References

Fawcett, J. et al., 1992, Nature, 360: 481-484.
Pino-otin, M.R. et al., 1995, Tissue. Antigens. 46: 32-44.
Simmons, D.L. et al., 1995, Cancer. Surv. 24: 141-155.
Jolly, C. et al., 2007, J. Virol. 81: 13916-13921.

Sino Biological Inc. liefert CD50 / ICAM-3 Antikörper ( FITC ) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über CD50 / ICAM-3 Antikörper ( FITC ) lesen Sie bitte: http://www.sinobiological.com/CD50-ICAM-3-Antibody-g-8810.html