CD171 / N-CAML1 / L1CAM Antikörper( FITC )

16.05.2012

CD171 / N-CAML1 / L1CAM Antikörper

Immunogen	Recombinant Human CD171 protein (Catalog#10140-H08H)
Reagents	FITC-conjugated rabbit monoclonal antibody
Clone ID	014
Ig Type	Rabbit IgG
Concentration	5 μl/Test, 0.1 mg/ml
Formulation	Aqueous solution containing 0.5% BSA and 0.1% sodium azide
Preparation	This antibody was obtained from a rabbit immunized with purified, recombinant Human CD171 / N-CAML1 / L1CAM (rh CD171 / N-CAML1 / L1CAM; Catalog#10140-H08H; NP_000416.1; Met 1-Glu 1120) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Usage Guide von CD171 / N-CAML1 / L1CAM Antikörper

Specificity

Human CD171 / N-CAML1 / L1CAM

Flow Cytometry

Flow cytometric analysis of anti-CD171 reactivity on HeLa cells.

Profile of anti-CD171 reactivity on HeLa cells analyzed by flow cytometry.

Flow cytometry was performed on a BD FACSCalibur flow cytometry system

Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.

Storage

This antibody is stable for 12 months from date of receipt when stored at 2℃- 8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Verwandte Produkte & Themen von CD171 / N-CAML1 / L1CAM Antikörper

CD171 / N-CAML1 / L1CAM Antibody Related Areas:

Neuroscience>>Synaptic Protein>>L1CAM/CD171

Stem Cell>>Neural Stem Cell (NSC)>>Neuronal Cell Markers>>L1CAM/CD171

Cancer>>Cancer Biomarkers>>L1CAM/CD171

Immunology>>Adaptive Immunity>>T Cell>>T Cell Migration/Adhesion>>L1CAM/CD171

Immunology>>Adhesion Molecule>>Cell Adhesion Molecule (IgSF CAM)>>L1CAM/CD171

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>L1CAM/CD171

Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Neutrophils>>L1CAM/CD171

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Monocyte Markers>>L1CAM/CD171

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>T Cell Migration/Adhesion>>L1CAM/CD171

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
L1CAM/CD171	Human	L1CAM/CD171/Fc Protein, Recombinant	10140-H03H
L1CAM/CD171	Human	L1CAM/CD171 Protein, Recombinant	10140-H08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human L1CAM/CD171	WB, ELISA	L1CAM/CD171 Antibody, Rabbit PAb	10140-RP01
Human L1CAM/CD171	WB, ELISA	L1CAM/CD171 Antibody, Rabbit PAb (Antigen Affinity Purified)	10140-RP02
Human L1CAM/CD171	FCM	CD171 / N-CAML1 / L1CAM Antibody ( FITC )	10140-R014-F

Hintergrund von CD171 / N-CAML1 / L1CAM Antikörper

L1 cell adhesion molecule (L1CAM), also designated as CD171, is a transmembrane cell adhesion molecule belonging to the immunoglobulin superfamily, and has been implicated in a variety of processes integral to the development of the nervous system, including neuronal migration, neurite outgrowth, and axon fasciculation. It is primarily expressed on projection axons of the central nervous system and peripheral nervous system, as well as on a few nonneuronal cell types, such as Schwann cells and lymphocytes. The 1257 amino acid (aa) residue precursor protein contains an extracellular domain consisting of six Ig-like C2-type domains and five fibronectin-type III domains and highly conserved transmembrane and cytoplasmic domains. L1CAM interacts with a variety of ligands including axonin-1, CD9, neurocan and intergrins, and it has been revealed that the RGD motif in the sixth Ig domain of L1CAM is a binding site for integrins, thus important for nuclear signaling. Disruption of L1CAM function causes three X-linked neurological syndromes, i.e. hydrocephalus, MASA syndrome (mental retardation, aphasia, shuffling gait and adducted thumbs) and spastic paraplegia syndrome. In addition, L1CAM is also overexpressed in a variety of human carcinomas and is associated with bad prognosis.

References

Rosenthal, A. et al., 1992, Nat. Genet. 2: 107-112.
Wong, E.V. et al., 1995, Trends. Neurosci. 18: 168-172.
Wong, E.V. et al., 1996, J. Biol. Chem. 271: 18217-18233.
Bao, S. et al., 2008, Cancer. Res. 68: 6043-6048.
Gast, D. et al., 2008, Exp. Cell. Res. 314: 2411-2418.

Sino Biological Inc. liefert CD171 / N-CAML1 / L1CAM Antikörper( FITC ) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über CD171 / N-CAML1 / L1CAM Antikörper( FITC ) lesen Sie bitte: http://www.sinobiological.com/CD171-N-CAML1-L1CAM-Antibody-g-8808.html