Danio rerio (zebrafish) EFNB2A / Ephrin B2a Protein

09.06.2013

Sino Biological Inc. liefert Danio rerio (zebrafish) EFNB2A / Ephrin B2a Protein mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Danio rerio (zebrafish) EFNB2A / Ephrin B2a Protein lesen Sie bitte:http://www.sinobiological.com/EFNB2A-Ephrin-B2a-Protein-Antibody-a-6256.html

Produkt-Information von EFNB2A / Ephrin B2a Protein

Synonym	EFNB2A, efnb2
Protein Construction	A DNA sequence encoding the zebrafish EFNB2A (O73874) (Met 1-Ala222) was expressed with the Fc region of human IgG1 at the C-terminus.
Source	Danio rerio (zebrafish)
Expression Host	Human Cells

QC Testing von EFNB2A / Ephrin B2a Protein

Purity	(16.2+75.4)% as determined by SDS-PAGE	SDS-PAGE: EFNB2A protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Leu 25
Molecular Mass	The recombinant zebrafish EFNB2A consists of 439 amino acids and has a calculated molecular mass of 48.9 kDa. It migrates as an 97 and 58 KDa band in SDS-PAGE under reducing conditions.
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements.

Usage Guide von EFNB2A / Ephrin B2a Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Beschreibung von EFNB2A / Ephrin B2a Protein

Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Efnb2a, together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.

References

Shaw KM. et al., 2006, Dev Dyn. 235 (7): 1753-60.
Kemp HA. et al., 2009, Dev Biol. 327 (2): 313-26.
Patten SA. et al., 2012, PLoS One. 7 (2): e31650.