Cynomolgus TNFRSF1B Protein (His Tag)

06.12.2012

Sino Biological Inc. liefert Cynomolgus TNFRSF1B Protein (His Tag) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über Cynomolgus TNFRSF1B Protein (His Tag) lesen Sie bitte: http://www.sinobiological.com/TNFRSF1B-Protein-g-9966.html

Produkt-Information von TNFRSF1B Protein

Synonym	TNFRSF1B
Protein Construction	A DNA sequence encoding the cynomolgus TNFRSF1B (F7EAE4) (Met1- Asp257) was expressed, fused with a polyhistidine tag at the C-terminus.
Source	Cynomolgus
Expression Host	Human Cells

QC Testing von TNFRSF1B Protein

Purity	> 95 % as determined by SDS-PAGE	SDS-PAGE: TNFRSF1B protein
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method
Stability	Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal	Leu 23
Molecular Mass	The recombinant cynomolgus TNFRSF1B comprises 246 amino acids and has a calculated molecular mass of 26.5 KDa. The apparent molecular mass of it is approximately 38 KDa respectively in SDS-PAGE.
Formulation	Lyophilized from sterile PBS, pH7.4. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

Usage Guide von TNFRSF1B Protein

Storage	Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution	A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Verwandte Produkte & Themen von TNFRSF1B Protein

Related Areas:

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>TNFR2/CD120b

Immunology>>Cytokine & Receptor>>TNF Superfamily>>TNFR2/CD120b

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells>>TNFR2/CD120b

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
TNFR2/CD120b	Human	TNFR2/CD120b/Fc Protein, Recombinant	10417-H03H
TNFR2/CD120b	Human	TNFR2/CD120b Protein, Recombinant	10417-H08H
TNFR2/CD120b	Mouse	TNFR2/CD120b/Fc Protein, Recombinant	50128-M02H
TNFR2/CD120b	Mouse	TNFR2/CD120b Protein, Recombinant	50128-M08H
TNFR2	Cynomolgus	TNFRSF1B Protein, Recombinant	90102-C08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human TNFR2/CD120b	WB, ELISA	Rabbit Monoclonal Antibody	10417-R006
Human TNFR2/CD120b	WB, ELISA	Rabbit Polyclonal Antibody	10417-RP01
Human TNFR2/CD120b	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10417-RP02
Mouse TNFR2/CD120b	WB, ELISA	TNFR2 / CD120b / TNFRSF1B Antibody	50128-RP01
Mouse TNFR2/CD120b	WB, ELISA	TNFR2 / CD120b / TNFRSF1B Antibody (Antigen Affinity Purified)	50128-RP02

Beschreibung von TNFRSF1B Protein

Tumor necrosis factor receptor superfamily member 1B, also known as TNFRII, TNFRSF1B, and CD120b, is a member to the TNFR (tumor necrosis factor receptor) superfamily characterized by cysteine-rich extracellular domains. TNFRII is expressed in fetal brain. The protein is produced naturally as a soluble form (sTNFRII). The soluble receptor inhibits TNFα action by competing with cell surface receptors in binding TNFα, thereby blocking its biologic effects. TNFRII is strongly expressed at the cartilage–pannus junction, and plays a major role in a subset of families with multiple cases of rheumatoid arthritis (RA). Further, high plasma levels of sTNFRII were significantly associated with increased incidence of coronary heart disease, independent of established cardiovascular risk factors, and seems to be useful for monitoring the inflammatory activity of sarcoidosis.

References

Philippe D. et al., 2002, Arthritis Care & Research. 46 (8): 2039-44.
Wassink T H.?et al., 2000, Molecular psychiatry. 5 (6): 678-82.
Alicia SC. et al., 2005, Molecular and Cellular Biology. 25 (11): 4716-26.
Ziegenhagen MW. et al., 2000, Journal of Internal Medicine. 248 (1): 33-41.
Iris Shai. et al., 2005, Diabetes Care. 28 (6): 1376-82.