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| Immunogen | Recombinant Human CEACAM5 / CD66e protein (Catalog#11077-H08H) |
| Antibody Type | Mouse Monoclonal Antibody ( Mouse mAb Service Platform ) |
| Clone ID | 2G6A10 |
| Ig Type |
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| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM5 / CD66e (rh CEACAM5 / CD66e; Catalog#11077-H08H; NP_004354.2; Met 1-Ala 685). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Specificity | Human CEACAM5 / CD66e | ||
| No cross-reactivity in ELISA with Human CEACAM1 Human CEACAM6 Human CEACAM3 Human CEACAM8 Human cell lysate (293 cell line) | |||
| Immunochemistry | IHC-P: 5-20 μg/mL
| ||
| Direct ELISA | This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CEACAM5. | ||
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Cancer>>Cancer Biomarkers>>CEACAM5/CD66e
Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>CEACAM5/CD66e
Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Granulocyte Markers>>CEACAM5/CD66e
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| CEACAM5/CD66e | Human | CEACAM5/CD66e/Fc Protein, Recombinant | 11077-H03H |
| CEACAM5/CD66e | Human | CEACAM5/CD66e Protein, Recombinant | 11077-H08H |
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human CEACAM5/CD66e | WB, ELISA | CEACAM5/CD66e Antibody, Rabbit PAb | 11077-RP01 |
| Human CEACAM5/CD66e | WB, ELISA | CEACAM5/CD66e Antibody, Rabbit PAb (Antigen Affinity Purified) | 11077-RP02 |
| Human CEACAM5/CD66e | WB | CEACAM5/CD66e Antibody, Mouse MAb | 11077-MM05 |
| Human CEACAM5/CD66e | ELISA | CEACAM5/CD66e Antibody, Mouse MAb | 11077-MM07 |
| Human CEACAM5/CD66e | ELISA, IHC-P | CEACAM5 / CD66e Antibody | 11077-MM08 |
CEACAM5, also known as CEA or D66e, belongs to the large CEACAM subfamily of immunoglobulin superfamily. CEACAM5 is expressed primarily by epithelial cells, and is synthesized as a glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. CEACAM5 contains one Ig-like V-type domain at the N-terminus, followed by six Ig-like C2-type domain and a GPI anchor, and exists as a homodimer. It functions as a homotypic intercellular adhesion molecule and serves as a widely used tumor marker, since it is expressed at higher levels in tumorous tissues than in corresponding normal tissues. CEACAM5 has also been shown to contribute to tumorigenicity by inhibiting cellular differentiation. In addition, CEACAM5 is identified as the host receptor for the Dr family of adhesins of E.Coli, and the binding of E.coli Dr adhesins leads to dissociation of the CEACAM5 homodimer.
Sino Biological Inc. liefert CEACAM5 / CD66e Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CEACAM5 / CD66e Antikörper lesen Sie bitte: http://www.sinobiological.com/CEACAM5-CD66e-Antibody-g-8780.html
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