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| Immunogen | Recombinant Mouse CD54 / ICAM1 protein (Catalog#50440-M08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 020 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD54 / ICAM1 (rM CD54 / ICAM1; Catalog#50440-M08H; NP_034623.1; Met 1-Asn 485). |
| Specificity | Mouse CD54 / ICAM1 | ||
| No cross-reactivity in ELISA with Human ICAM1 Human CD31 Human ICAM3 Human ICAM2 Mouse VCAM1 | |||
| Immunochemistry | IHC-P: 1-10 μg/mL
| ||
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Mouse ICAM1 in WB. | ||
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse ICAM1. | ||
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
ICAM1 (Inter-Cellular Adhesion Molecule 1), also known as CD54, is a type of intercellular adhesion molecule constitutely present in low concentrations in the membranes of leukocytes and endothelial cells. As an endothelial and leukocyte-associated transmembrane protein, ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration.ICAM1 is a ligand for LFA-1 (integrin). When activated, leukocytes bind to endothelial cells via ICAM-1/LFA-1 interaction and then transmigrate into tissues. Presence with heavy glycosylation and other structural characteristics, ICAM1 possesses binding sites for a number of immune-associated ligands and serves as the binding site for entry of the major group of human Rhinovirus (HRV) into various cell types. ICAM1 also becomes known for its affinity for Plasmodium falciparum-infected erythrocytes (PFIE), providing more of a role in infectious disease.
Sino Biological Inc. liefert CD54 / ICAM1 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CD54 / ICAM1 Antikörper lesen Sie bitte: http://www.sinobiological.com/CD54-ICAM1-Antibody-g-9158.html
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