CD20 / MS4A1 Antikörper ( FITC )

18.05.2012

Produkt-Information von CD20 / MS4A1 Antikörper

Immunogen	Human CD20 Transfected CHO Cells
Reagents	FITC-conjugated rabbit monoclonal antibody
Clone ID	001
Ig Type	Rabbit IgG
Concentration	5 μl/Test, 0.2 mg/ml
Formulation	Aqueous solution containing 0.5% BSA and 0.1% sodium azide
Preparation	This antibody was obtained from a rabbit immunized with purified, Human CD20 Transfected CHO Cells and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Usage Guide von CD20 / MS4A1 Antikörper

Specificity

Human CD20 / MS4A1

Flow Cytometry

Flow cytometric analysis of anti-CD20 reactivity on peripheral blood lymphocytes.

Profile of anti-CD20 reactivity on peripheral blood lymphocytes analyzed by flow cytometry.

Flow cytometry was performed on a BD FACSCalibur flow cytometry system

Please refer to www.sinobiological.com/Flow-Cytometry-FACS-Protocols-a-750.html for technical protocols.

Storage

This antibody is stable for 12 months from date of receipt when stored at 2℃- 8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Verwandte Produkte & Themen von CD20 / MS4A1 Antikörper

Antibody Related Areas:

Cancer>>Cancer Stem Cell (CSC)>>CD20/MS4A1

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hematopoietic Stem Cell Marker>>CD20/MS4A1

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD20/MS4A1

Immunology>>Cluster of Differentiation>>Hematopoietic Stem Cell CD Marker>>CD20/MS4A1

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD20/MS4A1	Human	CD20/MS4A1 Protein, Recombinant	11007-H04H
CD20/MS4A1	Human	CD20 / MS4A1 (aa 213-297) Protein, Recombinant	11007-H07H2
CD20/MS4A1	Ferret	CD20/MS4A1 Protein, Recombinant	60004-F08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CD20/MS4A1	FCM	CD20 / MS4A1 Antibody ( FITC )	11007-R001-F
Ferret CD20/MS4A1	WB, ELISA	CD20 / MS4A1 Antibody (Antigen Affinity Purified)	60004-RP02

Hintergrund von CD20 / MS4A1 Antikörper

B-lymphocyte antigen CD20, also known as B-lymphocyte surface antigen B1, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1 and MS4A1, is a multi-pass membrane protein which belongs to theMS4A family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 / MS4A1 is expressed on all stages of B cell development except the first and last. CD20 / MS4A1 is present from pre-pre B cells through memory cells, but not on either pro-B cells or plasma cells. It is found on B-cell lymphomas, hairy cell leukemia, B-cell chronic lymphocytic leukemia, and melanoma cancer stem cells. CD20 / MS4A1 is the target of the monoclonal antibodies (mAb) rituximab, Ibritumomab tiuxetan, and tositumomab, which are all active agents in the treatment of all B cell lymphomas and leukemias. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5); also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.

References

Tedder TF. et al.,1988, Proc Natl Acad Sci. 85 (1): 208-12.
Cragg MS. et al., 2005, Curr Dir Autoimmun. 8: 140-74.
Fang D. et al., 2005, Cancer Res. 65 (20): 9328-37.
Teeling JL. et al., 2006, J Immunol. 177: 362-371.

Sino Biological Inc. liefert CD20 / MS4A1 Antikörper ( FITC ) mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

Weitere Informationen über CD20 / MS4A1 Antikörper ( FITC ) lesen Sie bitte: http://www.sinobiological.com/CD20-MS4A1-Antibody-g-8819.html