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| Immunogen | Recombinant Mouse CD16 / FCGR3 protein (Catalog#50326-M08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 015 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD16 / FCGR3 (rM CD16 / FCGR3; Catalog#50326-M08H; P08508-1; Met 1-Thr 215). |
| Specificity | Mouse CD16 / FCGR3 |
| Has cross-reactivity in ELISA with Human CD64 No cross-reactivity in ELISA with Human CD32a Human CD32b Human CD16a Human CD16b Cynomolgus FCGR3 | |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Mouse FCGR3 in WB. Using a DAB detection system, the detection limit for Mouse FCGR3 is approximately 1 ng/lane under non-reducing conditions and 20 ng/lane under reducing conditions. |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse FCGR3. The detection limit for Mouse FCGR3 is approximately 0.00245 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
Low affinity immunoglobulin gamma Fc region receptor III, also known as IgG Fc receptor III, Fc-gamma RIII, FcRIII, FCGR3 and CD16, is a single-pass type I membrane protein. It is expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. Mouse CD16 / FCGR3 is a receptor for the Fc region of complexed immunoglobulins gamma. It is a low affinity receptor. It contains twoIg-like C2-type (immunoglobulin-like) domains. In human, CD16 is expressed as two distinct forms (CD16a and CD16b) encoded by two different highly homologous genes in a cell type-specific manner. CD16b is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas CD16a is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages.
Sino Biological Inc. liefert CD16 / FCGR3 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über CD16 / FCGR3 Antikörper lesen Sie bitte: http:www.sinobiological.com/CD16-FCGR3-Antibody-g-9198.html
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