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| Immunogen | Recombinant Human MESDC2 protein (Catalog#10949-H08H) |
| Antibody Type | Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform ) |
| Clone ID | 502 |
| Ig Type | Rabbit IgG |
| Formulation | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human MESDC2 (rh MESDC2; Catalog#10949-H08H; NP_055969.1; Ala 34-Lys 230). |
| Specificity | Human MESDC2 |
| Western blot | This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect Human MESDC2 in WB. Using a DAB detection system, the detection limit for Human MESDC2 is approximately 0.25 ng/lane under non-reducing conditions and reducing conditions. |
| Direct ELISA | This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human MESDC2. The detection limit for Human MESDC2 is approximately 0.00975 ng/well. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61 and MESDC2, is a member of the MESD family. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity resides in the N- and C-terminal unstructured regions. MESDC2 acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway. MESDC2 is essential for specification of embryonic polarity and mesoderm induction.
Sino Biological Inc. liefert MESDC2 Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.
Weitere Informationen über MESDC2 Antikörper lesen Sie bitte: http:www.sinobiological.com/MESDC2-Antibody-g-9197.html
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