CD147 / EMMPRIN / Basigin Antikörper

21.05.2012

Produkt-Information von CD147 / EMMPRIN / Basigin Antikörper

Immunogen	Recombinant Human CD147 / EMMPRIN / Basigin protein (Catalog#10186-H08H)
Antibody Type	Mouse Monoclonal Antibody ( Mouse mAb Service Platform )
Clone ID	9F7G6
Ig Type
Formulation	0.2 μm filtered solution in PBS with 5% trehalose
Preparation	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD147 / EMMPRIN / Basigin (rh CD147 / EMMPRIN / Basigin; Catalog#10186-H08H; NP_940991.1; Met 1-His 205). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Usage Guide von CD147 / EMMPRIN / Basigin Antikörper

Specificity

Human CD147 / EMMPRIN / Basigin

Immunochemistry

ICC/IF: 10-30 μg/mL

CD147-MM08-15ug-HeLa-IF Immunofluorescence

Immunofluorescence staining of human CD147 in HeLa cells with mouse monoclonal antibody (15 μg/mL). The image showing membrane staining of HeLa cells.

Direct ELISA

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human CD147.

Storage

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃.Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Verwandte Produkte & Themen von CD147 / EMMPRIN / Basigin Antikörper

Related Areas:

Enzyme>>Protease & Regulator>>Metalloprotease & Regulator>>CD147/EMMPRIN

Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hemangioblast>>Endothelial Cell Marker>>CD147/EMMPRIN

Cancer>>Cancer Biomarkers>>CD147/EMMPRIN

Immunology>>Adaptive Immunity>>T Cell>>T Cell Migration/Adhesion>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>B Cell CD Antigen>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>Dendritic Cell CD Antigen>>Dendritic Cell Adhesion>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>Granulocyte CD Antigen>>Basophils / Eosinophils / Granulocyte Markers /Neutrophils>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Monocyte Markers>>CD147/EMMPRIN

Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>T Cell Migration/Adhesion>>CD147/EMMPRIN

Proteins:

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
CD147/EMMPRIN	Human	CD147/EMMPRIN/Fc Protein, Recombinant	10186-H02H
CD147/EMMPRIN	Human	CD147/EMMPRIN Protein, Recombinant	10186-H08H
CD147/EMMPRIN	Human	CD147/EMMPRIN Protein, Recombinant	10186-HCCH
CD147/EMMPRIN	Mouse	CD147/EMMPRIN/Fc Protein, Recombinant	50332-M03H
CD147/EMMPRIN	Mouse	CD147/EMMPRIN Protein, Recombinant	50332-M08H

Antibodies:

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human CD147/EMMPRIN	WB, ELISA	Mouse Monoclonal Antibody	10186-MM05
Human CD147/EMMPRIN	ELISA, ICC/IF, IF	CD147 / EMMPRIN / Basigin Antibody	10186-MM08
Human CD147/EMMPRIN	FCM	CD147 / EMMPRIN / Basigin Antibody ( FITC )	10186-MM08-F
Human CD147/EMMPRIN	WB, ELISA, IHC	Rabbit Monoclonal Antibody	10186-R125
Human CD147/EMMPRIN	Flow Cytometry	CD147/EMMPRIN Antibody, Rabbit MAb	10186-R125F
Human CD147/EMMPRIN	WB, ELISA	Rabbit Polyclonal Antibody	10186-RP01
Human CD147/EMMPRIN	WB, ELISA	Rabbit Polyclonal Antibody	10186-RP02
Mouse CD147/EMMPRIN	WB, ELISA	CD147/EMMPRIN Antibody, Rabbit MAb	50332-R041
Mouse CD147/EMMPRIN	WB, ELISA	Rabbit Polyclonal Antibody	50332-RP01
Mouse CD147/EMMPRIN	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	50332-RP02

Hintergrund von CD147 / EMMPRIN / Basigin Antikörper

CD147, also known as BSG or EMMPRIN, is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation, and tumor progression. Enriched on the plasma memebrane of many human cancer (breast cancer, lymphoma, oral squamous cell carcinoma, glioma, melanoma, lung, bladder and kidney carcinomas) cells, CD147 induces the production and release of matrix metalloproteinases in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction.

References

Kanekura, T. et al., 1991, Cell. Struct. Funct. 16: 23-30.
Muramatsu,T. et al., 2003, Histol Histopathol. 18: 981-987.
Jin-Ming Yang. et al., 2006, J. Biol. Chem. 281: 9719-9727.
Hakuma, N. et al., 2007, Oncology. 72: 197-204.
Zheng HC. et al., 2006, Br. J. Cancer. 95: 1371-1378.
Yurchenko, V. et al., 2002, J. Biol. Chem. 277: 22959-22965.

Sino Biological Inc. liefert CD147 / EMMPRIN / Basigin Antikörper mit höherer Qualität und günstiger Kosten im Vergleich mit anderen globalen Lieferanten.

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